EID2 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	3 studies	21% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of EID2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	522.14	180 / 180	100%	35.27	430 / 430
uterus	100%	626.86	170 / 170	100%	43.62	459 / 459
esophagus	100%	684.35	1444 / 1445	100%	23.73	183 / 183
brain	100%	1122.17	2640 / 2642	100%	43.00	705 / 705
intestine	100%	640.99	966 / 966	100%	23.96	526 / 527
kidney	100%	596.35	89 / 89	100%	23.93	899 / 901
stomach	100%	519.68	358 / 359	100%	23.77	286 / 286
thymus	100%	662.44	652 / 653	100%	38.29	604 / 605
prostate	100%	585.74	245 / 245	100%	39.37	500 / 502
adrenal gland	100%	1254.41	258 / 258	100%	46.23	229 / 230
breast	100%	618.93	459 / 459	100%	34.92	1113 / 1118
liver	100%	388.44	226 / 226	100%	19.94	404 / 406
bladder	100%	571.24	21 / 21	99%	31.09	501 / 504
skin	100%	630.65	1809 / 1809	99%	31.35	469 / 472
lung	99%	601.67	574 / 578	100%	32.27	1155 / 1155
pancreas	97%	317.35	319 / 328	100%	30.30	178 / 178
lymph node	0%	0	0 / 0	100%	28.39	29 / 29
spleen	100%	688.30	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	30.19	45 / 45
ureter	0%	0	0 / 0	100%	36.36	1 / 1
adipose	100%	639.37	1203 / 1204	0%	0	0 / 0
blood vessel	100%	558.16	1331 / 1335	0%	0	0 / 0
muscle	100%	465.80	800 / 803	0%	0	0 / 0
heart	97%	438.90	837 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	18.44	76 / 80
peripheral blood	64%	209.65	591 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0060392	Biological process	negative regulation of SMAD protein signal transduction
GO_0030154	Biological process	cell differentiation
GO_0030512	Biological process	negative regulation of transforming growth factor beta receptor signaling pathway
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0007181	Biological process	transforming growth factor beta receptor complex assembly
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0042127	Biological process	regulation of cell population proliferation
GO_0007517	Biological process	muscle organ development
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding
GO_0046332	Molecular function	SMAD binding

Gene name	EID2
Protein name	EP300-interacting inhibitor of differentiation 2 (EID-2) (CREBBP/EP300 inhibitor 2) (EID-1-like inhibitor of differentiation 2) EID2 protein
Synonyms	CRI2
Description	FUNCTION: Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex. .
Accessions	Q6IPM4 ENST00000390658.4 [Q8N6I1-1] Q8N6I1

EID2 report