TBR1 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	33% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TBR1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	43%	977.31	1137 / 2642	41%	2.26	291 / 705
tonsil	0%	0	0 / 0	4%	0.11	2 / 45
uterus	1%	0.28	1 / 170	2%	0.19	10 / 459
adrenal gland	0%	0	0 / 258	1%	0.02	3 / 230
breast	0%	0.12	1 / 459	1%	0.04	9 / 1118
thymus	1%	0.68	4 / 653	0%	0.00	2 / 605
bladder	0%	0	0 / 21	1%	0.02	4 / 504
stomach	0%	0	0 / 359	1%	0.04	2 / 286
lung	0%	0	0 / 578	1%	0.01	7 / 1155
pancreas	0%	0	0 / 328	1%	0.01	1 / 178
intestine	0%	0.09	1 / 966	0%	0.01	1 / 527
ovary	0%	0	0 / 180	0%	0.00	1 / 430
heart	0%	0.17	2 / 861	0%	0	0 / 0
kidney	0%	0	0 / 89	0%	0.01	2 / 901
esophagus	0%	0.06	2 / 1445	0%	0	0 / 183
skin	0%	0.07	2 / 1809	0%	0	0 / 472
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0	0 / 406
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001708	Biological process	cell fate specification
GO_0021764	Biological process	amygdala development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0021902	Biological process	commitment of neuronal cell to specific neuron type in forebrain
GO_0006338	Biological process	chromatin remodeling
GO_0010092	Biological process	specification of animal organ identity
GO_1902667	Biological process	regulation of axon guidance
GO_0001661	Biological process	conditioned taste aversion
GO_0007420	Biological process	brain development
GO_0010975	Biological process	regulation of neuron projection development
GO_0030902	Biological process	hindbrain development
GO_0010467	Biological process	gene expression
GO_0021987	Biological process	cerebral cortex development
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0019901	Molecular function	protein kinase binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0031490	Molecular function	chromatin DNA binding
GO_0005515	Molecular function	protein binding

Gene name	TBR1
Protein name	T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56) T-box brain transcription factor 1
Synonyms
Description	FUNCTION: Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection . As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons (By similarity). .
Accessions	H7C0B1 ENST00000410035.1 [Q16650-2] Q16650 ENST00000389554.8 [Q16650-1] ENST00000411412.5

TBR1 report