ZBTB14 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZBTB14 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZBTB14 at tissue level.

III. Associated gene sets

GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0001822Biological processkidney development
GO_0060976Biological processcoronary vasculature development
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0003279Biological processcardiac septum development
GO_0003170Biological processheart valve development
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0016235Cellular componentaggresome
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameZBTB14
Protein nameZinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5)
Zinc finger and BTB domain containing 14
SynonymsZNF478
ZFP161
DescriptionFUNCTION: Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters. .

AccessionsENST00000615385.4
O43829
ENST00000651870.1
ENST00000582388.5
J3KRQ2
ENST00000614697.4
ENST00000357006.8
ENST00000578327.1
J3QL74
J3QLI2
ENST00000400143.7
ENST00000582135.5