Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| natural killer cell | 26 studies | 27% ± 10% | |
| plasma cell | 22 studies | 48% ± 23% | |
| CD16-positive, CD56-dim natural killer cell, human | 14 studies | 31% ± 10% | |
| CD16-negative, CD56-bright natural killer cell, human | 12 studies | 26% ± 8% | |
| plasmablast | 11 studies | 63% ± 19% | |
| B cell | 9 studies | 29% ± 8% | |
| ciliated cell | 8 studies | 25% ± 7% | |
| IgG plasma cell | 8 studies | 36% ± 15% | |
| astrocyte | 8 studies | 36% ± 20% | |
| precursor B cell | 6 studies | 64% ± 13% | |
| T cell | 6 studies | 30% ± 9% | |
| mature NK T cell | 5 studies | 27% ± 7% | |
| IgA plasma cell | 5 studies | 41% ± 20% | |
| pro-B cell | 5 studies | 51% ± 13% | |
| immature B cell | 5 studies | 38% ± 13% | |
| CD8-positive, alpha-beta T cell | 5 studies | 30% ± 10% | |
| CD4-positive, alpha-beta T cell | 4 studies | 25% ± 10% | |
| pericyte | 4 studies | 26% ± 5% | |
| gamma-delta T cell | 4 studies | 25% ± 14% | |
| exhausted T cell | 3 studies | 29% ± 9% | |
| germinal center B cell | 3 studies | 34% ± 8% | |
| IgM plasma cell | 3 studies | 44% ± 5% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 24% ± 11% | |
| plasmacytoid dendritic cell | 3 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of CD38 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 1039.05 | 564 / 578 | 79% | 9.61 | 909 / 1155 |
| brain | 81% | 686.64 | 2149 / 2642 | 93% | 31.44 | 659 / 705 |
| prostate | 92% | 1400.41 | 225 / 245 | 71% | 27.24 | 356 / 502 |
| esophagus | 79% | 286.13 | 1141 / 1445 | 56% | 7.67 | 103 / 183 |
| thymus | 96% | 643.19 | 629 / 653 | 28% | 11.07 | 169 / 605 |
| breast | 76% | 547.25 | 347 / 459 | 29% | 2.52 | 329 / 1118 |
| adrenal gland | 96% | 642.97 | 248 / 258 | 7% | 0.52 | 15 / 230 |
| intestine | 68% | 545.76 | 657 / 966 | 33% | 2.63 | 174 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 38.39 | 29 / 29 |
| spleen | 100% | 4242.58 | 241 / 241 | 0% | 0 | 0 / 0 |
| stomach | 50% | 167.31 | 181 / 359 | 48% | 6.09 | 136 / 286 |
| heart | 96% | 673.82 | 830 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 1957.88 | 882 / 929 | 0% | 0 | 0 / 0 |
| adipose | 95% | 842.59 | 1139 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 94% | 808.81 | 755 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 10.92 | 37 / 45 |
| liver | 65% | 367.19 | 148 / 226 | 16% | 1.58 | 65 / 406 |
| bladder | 48% | 137.67 | 10 / 21 | 33% | 3.09 | 168 / 504 |
| kidney | 47% | 150.90 | 42 / 89 | 30% | 2.25 | 266 / 901 |
| blood vessel | 67% | 407.65 | 892 / 1335 | 0% | 0 | 0 / 0 |
| uterus | 14% | 42.10 | 24 / 170 | 43% | 3.99 | 197 / 459 |
| skin | 5% | 11.74 | 83 / 1809 | 49% | 6.82 | 232 / 472 |
| ovary | 9% | 31.48 | 17 / 180 | 30% | 2.11 | 131 / 430 |
| pancreas | 5% | 9.89 | 15 / 328 | 34% | 2.56 | 60 / 178 |
| eye | 0% | 0 | 0 / 0 | 10% | 0.76 | 8 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032355 | Biological process | response to estradiol |
| GO_0097190 | Biological process | apoptotic signaling pathway |
| GO_0030307 | Biological process | positive regulation of cell growth |
| GO_0045779 | Biological process | negative regulation of bone resorption |
| GO_0007165 | Biological process | signal transduction |
| GO_0050853 | Biological process | B cell receptor signaling pathway |
| GO_0045907 | Biological process | positive regulation of vasoconstriction |
| GO_0033194 | Biological process | response to hydroperoxide |
| GO_0070555 | Biological process | response to interleukin-1 |
| GO_0060292 | Biological process | long-term synaptic depression |
| GO_0007565 | Biological process | female pregnancy |
| GO_0032024 | Biological process | positive regulation of insulin secretion |
| GO_0019674 | Biological process | NAD metabolic process |
| GO_0010977 | Biological process | negative regulation of neuron projection development |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0030890 | Biological process | positive regulation of B cell proliferation |
| GO_0014824 | Biological process | artery smooth muscle contraction |
| GO_0032526 | Biological process | response to retinoic acid |
| GO_0042100 | Biological process | B cell proliferation |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0032570 | Biological process | response to progesterone |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0009986 | Cellular component | cell surface |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0003953 | Molecular function | NAD+ nucleosidase activity |
| GO_0016849 | Molecular function | phosphorus-oxygen lyase activity |
| GO_0016740 | Molecular function | transferase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0061809 | Molecular function | NAD+ nucleotidase, cyclic ADP-ribose generating |
| Gene name | CD38 |
| Protein name | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (EC 3.2.2.-) (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase 1) (ADPRC 1) (Cyclic ADP-ribose hydrolase 1) (cADPR hydrolase 1) (T10) (CD antigen CD38) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (EC 2.4.99.20) (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase 1) (Cyclic ADP-ribose hydrolase 1) |
| Synonyms | |
| Description | FUNCTION: Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion . Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+) . Has cADPR hydrolase activity . . |
| Accessions | ENST00000226279.8 [P28907-1] ENST00000510674.1 H0Y950 P28907 ENST00000502843.5 [P28907-2] |