Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 15 studies | 32% ± 15% | |
| endothelial cell | 6 studies | 24% ± 5% | |
| epithelial cell | 6 studies | 41% ± 20% | |
| basal cell | 5 studies | 32% ± 15% | |
| oligodendrocyte precursor cell | 5 studies | 28% ± 12% | |
| GABAergic neuron | 4 studies | 34% ± 12% | |
| astrocyte | 4 studies | 26% ± 10% | |
| goblet cell | 4 studies | 25% ± 7% | |
| oligodendrocyte | 4 studies | 20% ± 4% | |
| retinal bipolar neuron | 3 studies | 23% ± 3% | |
| smooth muscle cell | 3 studies | 17% ± 1% | |
| B cell | 3 studies | 17% ± 2% | |
| retina horizontal cell | 3 studies | 27% ± 7% | |
| fibroblast | 3 studies | 17% ± 0% | |
| glutamatergic neuron | 3 studies | 49% ± 11% | |
| abnormal cell | 3 studies | 20% ± 2% | |
| intestinal crypt stem cell | 3 studies | 17% ± 1% | |
| transit amplifying cell | 3 studies | 22% ± 7% | |
| neuron | 3 studies | 29% ± 9% | |
| interneuron | 3 studies | 36% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 3492.62 | 21 / 21 | 100% | 40.95 | 504 / 504 |
| esophagus | 100% | 3577.02 | 1445 / 1445 | 100% | 35.49 | 183 / 183 |
| intestine | 100% | 3853.77 | 966 / 966 | 100% | 36.29 | 527 / 527 |
| lung | 100% | 3028.25 | 578 / 578 | 100% | 38.59 | 1155 / 1155 |
| prostate | 100% | 3643.53 | 245 / 245 | 100% | 45.11 | 502 / 502 |
| uterus | 100% | 3485.39 | 170 / 170 | 100% | 41.78 | 459 / 459 |
| breast | 100% | 3198.69 | 459 / 459 | 100% | 54.84 | 1116 / 1118 |
| brain | 100% | 2171.71 | 2634 / 2642 | 100% | 23.59 | 705 / 705 |
| stomach | 100% | 2738.07 | 359 / 359 | 100% | 34.15 | 285 / 286 |
| ovary | 100% | 3507.06 | 180 / 180 | 100% | 34.51 | 428 / 430 |
| thymus | 100% | 4035.23 | 653 / 653 | 100% | 41.78 | 602 / 605 |
| pancreas | 100% | 2370.11 | 328 / 328 | 99% | 30.90 | 177 / 178 |
| kidney | 100% | 2787.84 | 89 / 89 | 99% | 26.44 | 889 / 901 |
| skin | 100% | 3822.76 | 1809 / 1809 | 98% | 27.39 | 464 / 472 |
| adrenal gland | 100% | 2927.01 | 258 / 258 | 97% | 21.13 | 223 / 230 |
| liver | 100% | 1672.10 | 226 / 226 | 90% | 15.26 | 367 / 406 |
| adipose | 100% | 2667.57 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2972.65 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 28.56 | 29 / 29 |
| spleen | 100% | 3366.22 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 40.14 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 22.58 | 1 / 1 |
| muscle | 99% | 1589.89 | 797 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 1718.75 | 849 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2342.08 | 914 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 20.87 | 77 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0006915 | Biological process | apoptotic process |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_1902455 | Biological process | negative regulation of stem cell population maintenance |
| GO_1902459 | Biological process | positive regulation of stem cell population maintenance |
| GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0021762 | Biological process | substantia nigra development |
| GO_0070822 | Cellular component | Sin3-type complex |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0004407 | Molecular function | histone deacetylase activity |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| Gene name | SUDS3 |
| Protein name | SUDS3 protein Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog) |
| Synonyms | SDS3 SAP45 |
| Description | FUNCTION: Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. . |
| Accessions | Q9H7L9 Q2M2F3 ENST00000543473.2 Q52LB7 |