Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4082.55 | 1445 / 1445 | 100% | 18.11 | 183 / 183 |
breast | 100% | 5753.83 | 459 / 459 | 100% | 17.64 | 1113 / 1118 |
intestine | 100% | 4254.21 | 966 / 966 | 99% | 9.27 | 524 / 527 |
ovary | 100% | 5406.66 | 180 / 180 | 99% | 11.94 | 427 / 430 |
stomach | 100% | 3014.78 | 359 / 359 | 99% | 11.42 | 284 / 286 |
thymus | 100% | 4774.68 | 652 / 653 | 99% | 9.34 | 601 / 605 |
brain | 100% | 2861.36 | 2630 / 2642 | 100% | 13.09 | 702 / 705 |
lung | 100% | 7643.74 | 578 / 578 | 99% | 11.29 | 1142 / 1155 |
pancreas | 99% | 1893.31 | 325 / 328 | 99% | 7.78 | 177 / 178 |
bladder | 100% | 4351.57 | 21 / 21 | 98% | 7.83 | 493 / 504 |
uterus | 100% | 5993.12 | 170 / 170 | 97% | 8.66 | 447 / 459 |
prostate | 100% | 3887.52 | 245 / 245 | 97% | 8.94 | 485 / 502 |
skin | 100% | 6454.84 | 1809 / 1809 | 96% | 9.60 | 454 / 472 |
kidney | 100% | 2431.35 | 89 / 89 | 95% | 7.74 | 857 / 901 |
adrenal gland | 100% | 2659.08 | 258 / 258 | 93% | 4.86 | 213 / 230 |
liver | 100% | 1905.01 | 225 / 226 | 57% | 2.49 | 231 / 406 |
adipose | 100% | 5631.58 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4083.85 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 3443.69 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4953.48 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 13.37 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.40 | 1 / 1 |
peripheral blood | 99% | 6269.93 | 922 / 929 | 0% | 0 | 0 / 0 |
heart | 97% | 2173.47 | 838 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 89% | 5.07 | 71 / 80 |
lymph node | 0% | 0 | 0 / 0 | 86% | 6.37 | 25 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1903706 | Biological process | regulation of hemopoiesis |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0050793 | Biological process | regulation of developmental process |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0006334 | Biological process | nucleosome assembly |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0030099 | Biological process | myeloid cell differentiation |
GO_0051276 | Biological process | chromosome organization |
GO_1901796 | Biological process | regulation of signal transduction by p53 class mediator |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0090398 | Biological process | cellular senescence |
GO_0006473 | Biological process | protein acetylation |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0005730 | Cellular component | nucleolus |
GO_0000786 | Cellular component | nucleosome |
GO_0016607 | Cellular component | nuclear speck |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0016605 | Cellular component | PML body |
GO_0070776 | Cellular component | MOZ/MORF histone acetyltransferase complex |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0043997 | Molecular function | histone H4K12 acetyltransferase activity |
GO_0140297 | Molecular function | DNA-binding transcription factor binding |
GO_0036408 | Molecular function | histone H3K14 acetyltransferase activity |
GO_0003682 | Molecular function | chromatin binding |
GO_0046972 | Molecular function | histone H4K16 acetyltransferase activity |
GO_0010484 | Molecular function | histone H3 acetyltransferase activity |
GO_0003712 | Molecular function | transcription coregulator activity |
GO_0043996 | Molecular function | histone H4K8 acetyltransferase activity |
GO_0016407 | Molecular function | acetyltransferase activity |
GO_0043995 | Molecular function | histone H4K5 acetyltransferase activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0004402 | Molecular function | histone acetyltransferase activity |
GO_0003713 | Molecular function | transcription coactivator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | KAT6A |
Protein name | Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220) Lysine acetyltransferase 6A Histone acetyltransferase (EC 2.3.1.48) |
Synonyms | RUNXBP2 MYST3 ZNF220 MOZ |
Description | FUNCTION: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. . |
Accessions | ENST00000406337.6 ENST00000647746.1 A0A3B3ISU5 A0A3B3ISZ3 ENST00000649827.1 ENST00000426524.6 ENST00000396930.4 C9JJY6 A0A3B3IS53 A5PLL3 A0A3B3ITI3 ENST00000649817.1 ENST00000485568.5 ENST00000265713.8 A0A3F2YNX6 Q92794 ENST00000648335.1 |