KAT6A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1903706Biological processregulation of hemopoiesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0050793Biological processregulation of developmental process
GO_0010628Biological processpositive regulation of gene expression
GO_0006334Biological processnucleosome assembly
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0030099Biological processmyeloid cell differentiation
GO_0051276Biological processchromosome organization
GO_1901796Biological processregulation of signal transduction by p53 class mediator
GO_0006355Biological processregulation of DNA-templated transcription
GO_0090398Biological processcellular senescence
GO_0006473Biological processprotein acetylation
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0005730Cellular componentnucleolus
GO_0000786Cellular componentnucleosome
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0016605Cellular componentPML body
GO_0070776Cellular componentMOZ/MORF histone acetyltransferase complex
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0043997Molecular functionhistone H4K12 acetyltransferase activity
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0036408Molecular functionhistone H3K14 acetyltransferase activity
GO_0003682Molecular functionchromatin binding
GO_0046972Molecular functionhistone H4K16 acetyltransferase activity
GO_0010484Molecular functionhistone H3 acetyltransferase activity
GO_0003712Molecular functiontranscription coregulator activity
GO_0043996Molecular functionhistone H4K8 acetyltransferase activity
GO_0016407Molecular functionacetyltransferase activity
GO_0043995Molecular functionhistone H4K5 acetyltransferase activity
GO_0008270Molecular functionzinc ion binding
GO_0004402Molecular functionhistone acetyltransferase activity
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKAT6A
Protein nameHistone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Lysine acetyltransferase 6A
Histone acetyltransferase (EC 2.3.1.48)
SynonymsRUNXBP2
MYST3
ZNF220
MOZ
DescriptionFUNCTION: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. .

AccessionsENST00000406337.6
ENST00000647746.1
A0A3B3ISU5
A0A3B3ISZ3
ENST00000649827.1
ENST00000426524.6
ENST00000396930.4
C9JJY6
A0A3B3IS53
A5PLL3
A0A3B3ITI3
ENST00000649817.1
ENST00000485568.5
ENST00000265713.8
A0A3F2YNX6
Q92794
ENST00000648335.1