MYF6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MYF6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYF6 at tissue level.

III. Associated gene sets

GO_0007519Biological processskeletal muscle tissue development
GO_0060415Biological processmuscle tissue morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0045663Biological processpositive regulation of myoblast differentiation
GO_0042693Biological processmuscle cell fate commitment
GO_0001756Biological processsomitogenesis
GO_0035914Biological processskeletal muscle cell differentiation
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0048743Biological processpositive regulation of skeletal muscle fiber development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0072686Cellular componentmitotic spindle
GO_0005654Cellular componentnucleoplasm
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0070888Molecular functionE-box binding
GO_0046983Molecular functionprotein dimerization activity

IV. Literature review

[source]
Gene nameMYF6
Protein nameMyogenic factor 6 (Myf-6) (Class C basic helix-loop-helix protein 4) (bHLHc4) (Muscle-specific regulatory factor 4)
SynonymsBHLHC4
MRF4
DescriptionFUNCTION: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.

AccessionsP23409
ENST00000228641.4