ACTRT1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ACTRT1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ACTRT1 at tissue level.

III. Associated gene sets

GO_0008589Biological processregulation of smoothened signaling pathway
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0006355Biological processregulation of DNA-templated transcription
GO_0015629Cellular componentactin cytoskeleton
GO_0005856Cellular componentcytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameACTRT1
Protein nameActin-related protein T1 (ARP-T1)
SynonymsHSD27
ARPT1
DescriptionFUNCTION: Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression. .

AccessionsQ8TDG2
ENST00000371124.5