ZNF746 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051260Biological processprotein homooligomerization
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0051291Biological processprotein heterooligomerization
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF746
Protein nameZinc finger protein 746 (Parkin-interacting substrate) (PARIS)
Zinc finger protein 746
SynonymsFLJ31413
PARIS
hCG_1820621
DescriptionFUNCTION: Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. .

AccessionsC9JNZ9
Q6NUN9
A0A8J9FQ52
ENST00000461958.2
ENST00000458143.7
ENST00000644635.1
A0A2R8YDQ5
ENST00000685153.1 [Q6NUN9-2]
ENST00000340622.8 [Q6NUN9-1]