C1D report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0010468Biological processregulation of gene expression
GO_0000460Biological processmaturation of 5.8S rRNA
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0005730Cellular componentnucleolus
GO_0000176Cellular componentnuclear exosome (RNase complex)
GO_0005654Cellular componentnucleoplasm
GO_0000178Cellular componentexosome (RNase complex)
GO_0017053Cellular componenttranscription repressor complex
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0016922Molecular functionnuclear receptor binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameC1D
Protein nameNuclear nucleic acid-binding protein C1D (hC1D)
Nuclear nucleic acid-binding protein C1D
Synonyms
DescriptionFUNCTION: Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity). .

FUNCTION: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. .

AccessionsJ3KPZ4
ENST00000409302.1
ENST00000355848.7
ENST00000410067.8
ENST00000407324.5
Q13901