NR2F2 | OmnibusX

Name	Number of supported studies	Average coverage
pericyte	40 studies	55% ± 18%	Explore
fibroblast	34 studies	33% ± 15%	Explore
endothelial cell	33 studies	34% ± 13%	Explore
smooth muscle cell	29 studies	43% ± 15%	Explore
endothelial cell of lymphatic vessel	24 studies	52% ± 19%	Explore
connective tissue cell	13 studies	40% ± 18%	Explore
vein endothelial cell	12 studies	39% ± 15%	Explore
basal cell	10 studies	30% ± 13%	Explore
myofibroblast cell	8 studies	46% ± 16%	Explore
ciliated cell	6 studies	38% ± 13%	Explore
endothelial cell of vascular tree	6 studies	29% ± 23%	Explore
epithelial cell	6 studies	38% ± 15%	Explore
capillary endothelial cell	5 studies	24% ± 4%	Explore
abnormal cell	4 studies	33% ± 21%	Explore
GABAergic neuron	4 studies	25% ± 4%	Explore
goblet cell	4 studies	22% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	31% ± 4%	Explore
epithelial cell of proximal tubule	3 studies	23% ± 9%	Explore
kidney loop of Henle epithelial cell	3 studies	25% ± 5%	Explore
endothelial cell of sinusoid	3 studies	48% ± 26%	Explore
muscle cell	3 studies	45% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	5 studies	38% ± 12%	Explore
kidney	4 studies	29% ± 11%	Explore
intestine	4 studies	27% ± 11%	Explore
uterus	3 studies	43% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	99%	9006.69	243 / 245	100%	49.93	500 / 502
kidney	99%	10708.35	88 / 89	99%	73.03	888 / 901
stomach	100%	11493.91	358 / 359	98%	42.21	279 / 286
breast	100%	11018.33	459 / 459	97%	59.92	1086 / 1118
ovary	100%	39466.93	180 / 180	97%	43.58	417 / 430
intestine	98%	7236.62	950 / 966	98%	33.62	515 / 527
lung	99%	9976.25	575 / 578	94%	28.28	1080 / 1155
bladder	100%	7862.71	21 / 21	90%	26.18	455 / 504
thymus	100%	8649.15	650 / 653	89%	19.62	538 / 605
uterus	100%	21460.01	170 / 170	83%	31.38	382 / 459
adrenal gland	98%	7023.33	254 / 258	83%	20.94	192 / 230
esophagus	86%	8892.62	1241 / 1445	93%	34.53	170 / 183
skin	78%	4319.74	1411 / 1809	95%	38.06	447 / 472
liver	66%	2104.42	149 / 226	86%	22.48	350 / 406
pancreas	43%	1294.62	142 / 328	98%	45.07	174 / 178
spleen	100%	15468.58	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	18.87	1 / 1
adipose	100%	14758.47	1203 / 1204	0%	0	0 / 0
blood vessel	100%	17959.39	1333 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	85%	14.57	68 / 80
heart	83%	3916.99	715 / 861	0%	0	0 / 0
brain	16%	564.19	413 / 2642	56%	12.19	393 / 705
muscle	71%	2389.08	569 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	69%	18.15	31 / 45
lymph node	0%	0	0 / 0	52%	7.13	15 / 29
peripheral blood	2%	104.80	21 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0032355	Biological process	response to estradiol
GO_0001893	Biological process	maternal placenta development
GO_0007519	Biological process	skeletal muscle tissue development
GO_0060838	Biological process	lymphatic endothelial cell fate commitment
GO_0030900	Biological process	forebrain development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0030522	Biological process	intracellular receptor signaling pathway
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0009956	Biological process	radial pattern formation
GO_0060707	Biological process	trophoblast giant cell differentiation
GO_0001937	Biological process	negative regulation of endothelial cell proliferation
GO_0009566	Biological process	fertilization
GO_0003084	Biological process	positive regulation of systemic arterial blood pressure
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0060674	Biological process	placenta blood vessel development
GO_0030154	Biological process	cell differentiation
GO_1904936	Biological process	interneuron migration
GO_0009952	Biological process	anterior/posterior pattern specification
GO_0010596	Biological process	negative regulation of endothelial cell migration
GO_0048514	Biological process	blood vessel morphogenesis
GO_0048856	Biological process	anatomical structure development
GO_0045736	Biological process	negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO_0008585	Biological process	female gonad development
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0042803	Molecular function	protein homodimerization activity
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0043565	Molecular function	sequence-specific DNA binding
GO_0004879	Molecular function	nuclear receptor activity
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0001972	Molecular function	retinoic acid binding
GO_0008270	Molecular function	zinc ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	NR2F2
Protein name	COUP transcription factor 2 (COUP transcription factor II) (Nuclear receptor subfamily 2 group F member 2) Nuclear receptor subfamily 2 group F member 2 COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2)
Synonyms	TFCOUP2 ARP1
Description	FUNCTION: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development . .
Accessions	ENST00000394171.6 [P24468-3] H3BTC2 P24468 ENST00000421109.6 [P24468-2] ENST00000559679.1 ENST00000453270.2 [P24468-3] ENST00000394166.8 [P24468-1] F1D8R0

NR2F2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review