I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| kidney distal convoluted tubule epithelial cell | 6 studies | 38% ± 9% | |
| retina horizontal cell | 5 studies | 44% ± 17% | |
| renal principal cell | 3 studies | 23% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| kidney distal convoluted tubule epithelial cell | 6 studies | 38% ± 9% | |
| retina horizontal cell | 5 studies | 44% ± 17% | |
| renal principal cell | 3 studies | 23% ± 6% |
Insufficient scRNA-seq data for expression of LHX1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 1289.55 | 89 / 89 | 13% | 1.56 | 114 / 901 |
| ovary | 7% | 5.42 | 12 / 180 | 60% | 22.16 | 257 / 430 |
| brain | 45% | 810.02 | 1181 / 2642 | 18% | 0.60 | 130 / 705 |
| skin | 0% | 0.04 | 3 / 1809 | 31% | 0.96 | 145 / 472 |
| uterus | 4% | 9.26 | 7 / 170 | 15% | 2.25 | 69 / 459 |
| esophagus | 0% | 0.16 | 4 / 1445 | 19% | 1.26 | 34 / 183 |
| bladder | 0% | 0 | 0 / 21 | 13% | 0.65 | 65 / 504 |
| peripheral blood | 12% | 3.37 | 108 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.24 | 5 / 45 |
| pancreas | 0% | 0.06 | 1 / 328 | 11% | 0.30 | 19 / 178 |
| lung | 0% | 0 | 0 / 578 | 9% | 0.49 | 102 / 1155 |
| adrenal gland | 0% | 3.14 | 1 / 258 | 8% | 0.27 | 19 / 230 |
| breast | 0% | 0 | 0 / 459 | 8% | 0.69 | 94 / 1118 |
| intestine | 0% | 0 | 0 / 966 | 4% | 0.11 | 22 / 527 |
| stomach | 0% | 0 | 0 / 359 | 3% | 0.19 | 9 / 286 |
| liver | 0% | 0.09 | 1 / 226 | 2% | 0.05 | 7 / 406 |
| prostate | 2% | 3.43 | 5 / 245 | 0% | 0 | 0 / 502 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0.12 | 3 / 605 |
| spleen | 0% | 0.09 | 1 / 241 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.02 | 1 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.03 | 1 / 861 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0.01 | 1 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.04 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0010468 | Biological process | regulation of gene expression |
| GO_0001658 | Biological process | branching involved in ureteric bud morphogenesis |
| GO_0060059 | Biological process | embryonic retina morphogenesis in camera-type eye |
| GO_0060322 | Biological process | head development |
| GO_0001655 | Biological process | urogenital system development |
| GO_0090009 | Biological process | primitive streak formation |
| GO_0001705 | Biological process | ectoderm formation |
| GO_2000744 | Biological process | positive regulation of anterior head development |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0048703 | Biological process | embryonic viscerocranium morphogenesis |
| GO_0060068 | Biological process | vagina development |
| GO_0072224 | Biological process | metanephric glomerulus development |
| GO_0021549 | Biological process | cerebellum development |
| GO_0001706 | Biological process | endoderm formation |
| GO_0035502 | Biological process | metanephric part of ureteric bud development |
| GO_0097477 | Biological process | lateral motor column neuron migration |
| GO_0001657 | Biological process | ureteric bud development |
| GO_0009948 | Biological process | anterior/posterior axis specification |
| GO_2000543 | Biological process | positive regulation of gastrulation |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0001822 | Biological process | kidney development |
| GO_0060067 | Biological process | cervix development |
| GO_0072283 | Biological process | metanephric renal vesicle morphogenesis |
| GO_0040019 | Biological process | positive regulation of embryonic development |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0048793 | Biological process | pronephros development |
| GO_0009653 | Biological process | anatomical structure morphogenesis |
| GO_0035847 | Biological process | uterine epithelium development |
| GO_0072197 | Biological process | ureter morphogenesis |
| GO_0072077 | Biological process | renal vesicle morphogenesis |
| GO_0007399 | Biological process | nervous system development |
| GO_0010842 | Biological process | retina layer formation |
| GO_0035849 | Biological process | nephric duct elongation |
| GO_0061205 | Biological process | paramesonephric duct development |
| GO_0021527 | Biological process | spinal cord association neuron differentiation |
| GO_0021702 | Biological process | cerebellar Purkinje cell differentiation |
| GO_0097379 | Biological process | dorsal spinal cord interneuron posterior axon guidance |
| GO_0032525 | Biological process | somite rostral/caudal axis specification |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0048382 | Biological process | mesendoderm development |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0021937 | Biological process | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation |
| GO_0060065 | Biological process | uterus development |
| GO_0072278 | Biological process | metanephric comma-shaped body morphogenesis |
| GO_0090190 | Biological process | positive regulation of branching involved in ureteric bud morphogenesis |
| GO_0009952 | Biological process | anterior/posterior pattern specification |
| GO_0060066 | Biological process | oviduct development |
| GO_0072178 | Biological process | nephric duct morphogenesis |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0001702 | Biological process | gastrulation with mouth forming second |
| GO_2000768 | Biological process | positive regulation of nephron tubule epithelial cell differentiation |
| GO_0009791 | Biological process | post-embryonic development |
| GO_0021871 | Biological process | forebrain regionalization |
| GO_0021517 | Biological process | ventral spinal cord development |
| GO_0072284 | Biological process | metanephric S-shaped body morphogenesis |
| GO_0035846 | Biological process | oviduct epithelium development |
| GO_0009953 | Biological process | dorsal/ventral pattern formation |
| GO_0072050 | Biological process | S-shaped body morphogenesis |
| GO_0009880 | Biological process | embryonic pattern specification |
| GO_0048646 | Biological process | anatomical structure formation involved in morphogenesis |
| GO_0008045 | Biological process | motor neuron axon guidance |
| GO_0060429 | Biological process | epithelium development |
| GO_0072177 | Biological process | mesonephric duct development |
| GO_0044344 | Biological process | cellular response to fibroblast growth factor stimulus |
| GO_0007389 | Biological process | pattern specification process |
| GO_0021537 | Biological process | telencephalon development |
| GO_0072049 | Biological process | comma-shaped body morphogenesis |
| GO_0005634 | Cellular component | nucleus |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0000785 | Cellular component | chromatin |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0000987 | Molecular function | cis-regulatory region sequence-specific DNA binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| Gene name | LHX1 |
| Protein name | LIM/homeobox protein Lhx1 LIM/homeobox protein Lhx1 (Homeobox protein Lim-1) LIM homeobox 1 LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1) |
| Synonyms | LIM-1 LIM1 |
| Description | FUNCTION: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. . FUNCTION: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. . |
| Accessions | P48742 A0A0J9YX49 Q58F18 ENST00000620305.2 ENST00000621767.1 ENST00000633397.1 ENST00000614239.1 A0A087WY40 |
