Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 49% ± 21% | |
endothelial cell | 19 studies | 32% ± 15% | |
oligodendrocyte | 14 studies | 40% ± 15% | |
oligodendrocyte precursor cell | 13 studies | 46% ± 18% | |
microglial cell | 13 studies | 39% ± 13% | |
glutamatergic neuron | 12 studies | 54% ± 23% | |
GABAergic neuron | 11 studies | 53% ± 23% | |
macrophage | 11 studies | 33% ± 14% | |
fibroblast | 10 studies | 30% ± 15% | |
pericyte | 9 studies | 33% ± 17% | |
epithelial cell | 8 studies | 29% ± 12% | |
B cell | 8 studies | 20% ± 6% | |
adipocyte | 8 studies | 29% ± 8% | |
mast cell | 8 studies | 22% ± 6% | |
smooth muscle cell | 8 studies | 28% ± 9% | |
retinal cone cell | 7 studies | 41% ± 19% | |
retinal rod cell | 7 studies | 37% ± 20% | |
neuron | 6 studies | 45% ± 15% | |
interneuron | 6 studies | 64% ± 20% | |
myeloid cell | 6 studies | 22% ± 4% | |
dendritic cell | 6 studies | 21% ± 4% | |
endothelial cell of lymphatic vessel | 6 studies | 31% ± 12% | |
amacrine cell | 5 studies | 41% ± 16% | |
ciliated cell | 5 studies | 24% ± 9% | |
Mueller cell | 5 studies | 49% ± 20% | |
monocyte | 5 studies | 26% ± 7% | |
type I pneumocyte | 5 studies | 22% ± 7% | |
type II pneumocyte | 5 studies | 23% ± 7% | |
granule cell | 4 studies | 52% ± 6% | |
cardiac muscle cell | 4 studies | 25% ± 1% | |
retina horizontal cell | 4 studies | 37% ± 13% | |
club cell | 4 studies | 26% ± 9% | |
GABAergic interneuron | 3 studies | 49% ± 1% | |
glial cell | 3 studies | 30% ± 15% | |
progenitor cell | 3 studies | 46% ± 13% | |
GABAergic amacrine cell | 3 studies | 48% ± 12% | |
ON-bipolar cell | 3 studies | 35% ± 14% | |
glycinergic amacrine cell | 3 studies | 43% ± 6% | |
retinal ganglion cell | 3 studies | 36% ± 12% | |
rod bipolar cell | 3 studies | 34% ± 17% | |
hepatocyte | 3 studies | 30% ± 8% | |
retinal pigment epithelial cell | 3 studies | 41% ± 19% | |
abnormal cell | 3 studies | 27% ± 14% | |
ependymal cell | 3 studies | 46% ± 13% | |
T cell | 3 studies | 20% ± 2% | |
alveolar macrophage | 3 studies | 30% ± 11% | |
lymphocyte | 3 studies | 24% ± 8% | |
basal cell | 3 studies | 33% ± 18% | |
goblet cell | 3 studies | 31% ± 16% | |
transit amplifying cell | 3 studies | 39% ± 23% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2073.54 | 1445 / 1445 | 100% | 15.14 | 183 / 183 |
prostate | 100% | 2344.91 | 245 / 245 | 100% | 7.24 | 502 / 502 |
breast | 100% | 2566.54 | 459 / 459 | 99% | 10.41 | 1112 / 1118 |
uterus | 100% | 3142.30 | 170 / 170 | 99% | 6.95 | 456 / 459 |
ovary | 100% | 2777.71 | 180 / 180 | 99% | 8.45 | 426 / 430 |
thymus | 100% | 2539.94 | 652 / 653 | 99% | 6.65 | 599 / 605 |
bladder | 100% | 2431.48 | 21 / 21 | 99% | 7.23 | 498 / 504 |
brain | 100% | 2564.23 | 2640 / 2642 | 99% | 10.64 | 697 / 705 |
lung | 100% | 2562.91 | 578 / 578 | 98% | 8.08 | 1135 / 1155 |
stomach | 100% | 1475.53 | 359 / 359 | 98% | 9.97 | 281 / 286 |
intestine | 100% | 2428.61 | 966 / 966 | 97% | 7.42 | 513 / 527 |
skin | 100% | 1999.78 | 1808 / 1809 | 96% | 6.82 | 452 / 472 |
kidney | 100% | 1535.73 | 89 / 89 | 95% | 6.30 | 859 / 901 |
pancreas | 98% | 927.60 | 321 / 328 | 97% | 5.37 | 172 / 178 |
adrenal gland | 100% | 1682.11 | 258 / 258 | 88% | 4.36 | 202 / 230 |
liver | 100% | 871.95 | 225 / 226 | 74% | 2.93 | 300 / 406 |
blood vessel | 100% | 2473.59 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 7.59 | 29 / 29 |
spleen | 100% | 2989.51 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 7.67 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.93 | 1 / 1 |
adipose | 100% | 2457.47 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 1400.29 | 799 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1177.65 | 843 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 1687.43 | 883 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 74% | 2.85 | 59 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1902895 | Biological process | positive regulation of miRNA transcription |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0000979 | Molecular function | RNA polymerase II core promoter sequence-specific DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0005515 | Molecular function | protein binding |
GO_0043565 | Molecular function | sequence-specific DNA binding |
Gene name | POU2F1 |
Protein name | Oct-1B (POU class 2 homeobox 1) POU class 2 homeobox 1 POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) POU domain protein |
Synonyms | OCT1 Oct1Z oct-1B OTF1 |
Description | FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. .; FUNCTION: (Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . |
Accessions | ENST00000367862.9 [P14859-2] A0A0P0GE07 ENST00000367866.7 [P14859-6] A0A0A0MT46 ENST00000560232.6 ENST00000442313.5 P14859 A0A8A2IE78 Q16075 ENST00000271411.8 ENST00000443275.2 ENST00000541643.7 [P14859-1] ENST00000429375.6 [P14859-5] A0A345S7Y2 ENST00000420254.7 A0A0C4DG88 A0A0A0MSV5 |