Name | Number of supported studies | Average coverage | |
---|---|---|---|
CD8-positive, alpha-beta T cell | 27 studies | 50% ± 24% | |
T cell | 19 studies | 33% ± 14% | |
natural killer cell | 17 studies | 41% ± 20% | |
mucosal invariant T cell | 16 studies | 68% ± 21% | |
CD16-negative, CD56-bright natural killer cell, human | 15 studies | 56% ± 21% | |
gamma-delta T cell | 12 studies | 32% ± 11% | |
mature NK T cell | 12 studies | 40% ± 21% | |
effector memory CD8-positive, alpha-beta T cell | 9 studies | 59% ± 23% | |
CD8-positive, alpha-beta memory T cell | 9 studies | 47% ± 24% | |
effector CD8-positive, alpha-beta T cell | 8 studies | 45% ± 24% | |
CD4-positive, alpha-beta T cell | 7 studies | 25% ± 5% | |
exhausted T cell | 5 studies | 78% ± 29% | |
central memory CD8-positive, alpha-beta T cell | 4 studies | 45% ± 11% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 4 studies | 43% ± 13% | |
double negative thymocyte | 4 studies | 55% ± 28% | |
innate lymphoid cell | 4 studies | 55% ± 8% | |
effector memory CD8-positive, alpha-beta T cell, terminally differentiated | 4 studies | 24% ± 6% | |
effector CD4-positive, alpha-beta T cell | 3 studies | 28% ± 6% |
Insufficient scRNA-seq data for expression of GZMK at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 98% | 117.53 | 569 / 578 | 73% | 3.49 | 839 / 1155 |
breast | 72% | 33.64 | 330 / 459 | 71% | 4.63 | 792 / 1118 |
uterus | 91% | 51.28 | 155 / 170 | 51% | 2.40 | 232 / 459 |
prostate | 81% | 58.69 | 199 / 245 | 56% | 1.64 | 283 / 502 |
stomach | 81% | 38.67 | 290 / 359 | 51% | 2.53 | 145 / 286 |
liver | 88% | 40.41 | 200 / 226 | 35% | 1.53 | 141 / 406 |
kidney | 45% | 44.90 | 40 / 89 | 73% | 8.29 | 655 / 901 |
thymus | 72% | 84.76 | 469 / 653 | 44% | 2.65 | 264 / 605 |
lymph node | 0% | 0 | 0 / 0 | 100% | 51.53 | 29 / 29 |
spleen | 100% | 835.60 | 241 / 241 | 0% | 0 | 0 / 0 |
intestine | 60% | 72.62 | 578 / 966 | 40% | 1.44 | 210 / 527 |
bladder | 52% | 66.14 | 11 / 21 | 39% | 1.52 | 197 / 504 |
adipose | 89% | 74.80 | 1074 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 19% | 4.70 | 63 / 328 | 66% | 3.49 | 118 / 178 |
peripheral blood | 85% | 428.15 | 786 / 929 | 0% | 0 | 0 / 0 |
skin | 20% | 5.78 | 360 / 1809 | 65% | 6.19 | 305 / 472 |
tonsil | 0% | 0 | 0 / 0 | 82% | 5.06 | 37 / 45 |
ovary | 41% | 20.32 | 73 / 180 | 40% | 0.99 | 170 / 430 |
adrenal gland | 57% | 20.99 | 147 / 258 | 14% | 0.25 | 32 / 230 |
esophagus | 39% | 14.09 | 562 / 1445 | 31% | 0.96 | 57 / 183 |
blood vessel | 65% | 50.05 | 868 / 1335 | 0% | 0 | 0 / 0 |
heart | 35% | 14.31 | 301 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 20% | 1.61 | 16 / 80 |
brain | 9% | 2.79 | 240 / 2642 | 10% | 0.31 | 72 / 705 |
muscle | 4% | 1.13 | 33 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006508 | Biological process | proteolysis |
GO_0030141 | Cellular component | secretory granule |
GO_0005576 | Cellular component | extracellular region |
GO_0008236 | Molecular function | serine-type peptidase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | GZMK |
Protein name | Granzyme K (EC 3.4.21.-) (Fragmentin-3) (Granzyme-3) (NK-tryptase-2) (NK-Tryp-2) |
Synonyms | TRYP2 |
Description | |
Accessions | P49863 ENST00000231009.3 |