Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| CD8-positive, alpha-beta T cell | 27 studies | 50% ± 24% | |
| T cell | 19 studies | 33% ± 14% | |
| natural killer cell | 17 studies | 41% ± 20% | |
| mucosal invariant T cell | 16 studies | 68% ± 21% | |
| CD16-negative, CD56-bright natural killer cell, human | 15 studies | 56% ± 21% | |
| gamma-delta T cell | 12 studies | 32% ± 11% | |
| mature NK T cell | 12 studies | 40% ± 21% | |
| effector memory CD8-positive, alpha-beta T cell | 9 studies | 59% ± 23% | |
| CD8-positive, alpha-beta memory T cell | 9 studies | 47% ± 24% | |
| effector CD8-positive, alpha-beta T cell | 8 studies | 45% ± 24% | |
| CD4-positive, alpha-beta T cell | 7 studies | 25% ± 5% | |
| exhausted T cell | 5 studies | 78% ± 29% | |
| central memory CD8-positive, alpha-beta T cell | 4 studies | 45% ± 11% | |
| naive thymus-derived CD8-positive, alpha-beta T cell | 4 studies | 43% ± 13% | |
| double negative thymocyte | 4 studies | 55% ± 28% | |
| innate lymphoid cell | 4 studies | 55% ± 8% | |
| effector memory CD8-positive, alpha-beta T cell, terminally differentiated | 4 studies | 24% ± 6% | |
| effector CD4-positive, alpha-beta T cell | 3 studies | 28% ± 6% |
Insufficient scRNA-seq data for expression of GZMK at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 117.53 | 569 / 578 | 73% | 3.49 | 839 / 1155 |
| breast | 72% | 33.64 | 330 / 459 | 71% | 4.63 | 792 / 1118 |
| uterus | 91% | 51.28 | 155 / 170 | 51% | 2.40 | 232 / 459 |
| prostate | 81% | 58.69 | 199 / 245 | 56% | 1.64 | 283 / 502 |
| stomach | 81% | 38.67 | 290 / 359 | 51% | 2.53 | 145 / 286 |
| liver | 88% | 40.41 | 200 / 226 | 35% | 1.53 | 141 / 406 |
| kidney | 45% | 44.90 | 40 / 89 | 73% | 8.29 | 655 / 901 |
| thymus | 72% | 84.76 | 469 / 653 | 44% | 2.65 | 264 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 51.53 | 29 / 29 |
| spleen | 100% | 835.60 | 241 / 241 | 0% | 0 | 0 / 0 |
| intestine | 60% | 72.62 | 578 / 966 | 40% | 1.44 | 210 / 527 |
| bladder | 52% | 66.14 | 11 / 21 | 39% | 1.52 | 197 / 504 |
| adipose | 89% | 74.80 | 1074 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 19% | 4.70 | 63 / 328 | 66% | 3.49 | 118 / 178 |
| peripheral blood | 85% | 428.15 | 786 / 929 | 0% | 0 | 0 / 0 |
| skin | 20% | 5.78 | 360 / 1809 | 65% | 6.19 | 305 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 5.06 | 37 / 45 |
| ovary | 41% | 20.32 | 73 / 180 | 40% | 0.99 | 170 / 430 |
| adrenal gland | 57% | 20.99 | 147 / 258 | 14% | 0.25 | 32 / 230 |
| esophagus | 39% | 14.09 | 562 / 1445 | 31% | 0.96 | 57 / 183 |
| blood vessel | 65% | 50.05 | 868 / 1335 | 0% | 0 | 0 / 0 |
| heart | 35% | 14.31 | 301 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 20% | 1.61 | 16 / 80 |
| brain | 9% | 2.79 | 240 / 2642 | 10% | 0.31 | 72 / 705 |
| muscle | 4% | 1.13 | 33 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006508 | Biological process | proteolysis |
| GO_0030141 | Cellular component | secretory granule |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | GZMK |
| Protein name | Granzyme K (EC 3.4.21.-) (Fragmentin-3) (Granzyme-3) (NK-tryptase-2) (NK-Tryp-2) |
| Synonyms | TRYP2 |
| Description | |
| Accessions | P49863 ENST00000231009.3 |