Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 38 studies | 54% ± 20% | |
CD8-positive, alpha-beta T cell | 26 studies | 46% ± 21% | |
mature NK T cell | 17 studies | 63% ± 24% | |
CD16-positive, CD56-dim natural killer cell, human | 15 studies | 63% ± 17% | |
T cell | 14 studies | 34% ± 13% | |
CD16-negative, CD56-bright natural killer cell, human | 13 studies | 30% ± 12% | |
gamma-delta T cell | 12 studies | 45% ± 17% | |
CD8-positive, alpha-beta memory T cell | 11 studies | 39% ± 16% | |
effector memory CD8-positive, alpha-beta T cell | 10 studies | 44% ± 20% | |
effector CD8-positive, alpha-beta T cell | 9 studies | 51% ± 24% | |
effector memory CD8-positive, alpha-beta T cell, terminally differentiated | 5 studies | 76% ± 9% | |
exhausted T cell | 5 studies | 32% ± 9% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 4 studies | 44% ± 24% | |
CD4-positive, alpha-beta T cell | 3 studies | 42% ± 31% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 14 studies | 21% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 99% | 274.49 | 573 / 578 | 86% | 15.40 | 996 / 1155 |
thymus | 81% | 60.44 | 528 / 653 | 69% | 9.23 | 419 / 605 |
prostate | 82% | 51.54 | 202 / 245 | 62% | 4.43 | 309 / 502 |
kidney | 63% | 36.61 | 56 / 89 | 79% | 16.65 | 714 / 901 |
liver | 82% | 57.90 | 185 / 226 | 58% | 6.04 | 234 / 406 |
stomach | 79% | 46.85 | 284 / 359 | 60% | 10.41 | 172 / 286 |
breast | 68% | 47.10 | 313 / 459 | 64% | 7.90 | 714 / 1118 |
uterus | 56% | 26.71 | 96 / 170 | 69% | 17.01 | 319 / 459 |
bladder | 71% | 54.71 | 15 / 21 | 54% | 9.63 | 272 / 504 |
intestine | 50% | 28.33 | 485 / 966 | 55% | 6.99 | 290 / 527 |
lymph node | 0% | 0 | 0 / 0 | 100% | 108.86 | 29 / 29 |
spleen | 100% | 680.62 | 241 / 241 | 0% | 0 | 0 / 0 |
esophagus | 46% | 20.16 | 671 / 1445 | 48% | 5.45 | 88 / 183 |
tonsil | 0% | 0 | 0 / 0 | 91% | 41.08 | 41 / 45 |
peripheral blood | 90% | 2497.03 | 832 / 929 | 0% | 0 | 0 / 0 |
pancreas | 20% | 6.35 | 65 / 328 | 67% | 8.37 | 120 / 178 |
skin | 15% | 4.91 | 280 / 1809 | 69% | 19.97 | 324 / 472 |
adrenal gland | 54% | 23.66 | 140 / 258 | 27% | 2.31 | 63 / 230 |
adipose | 78% | 70.01 | 936 / 1204 | 0% | 0 | 0 / 0 |
ovary | 23% | 10.14 | 41 / 180 | 44% | 3.70 | 188 / 430 |
blood vessel | 47% | 28.34 | 633 / 1335 | 0% | 0 | 0 / 0 |
heart | 45% | 19.76 | 390 / 861 | 0% | 0 | 0 / 0 |
brain | 26% | 10.60 | 683 / 2642 | 18% | 1.49 | 126 / 705 |
eye | 0% | 0 | 0 / 0 | 26% | 2.91 | 21 / 80 |
muscle | 14% | 4.73 | 116 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006915 | Biological process | apoptotic process |
GO_0031640 | Biological process | killing of cells of another organism |
GO_0006508 | Biological process | proteolysis |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0044194 | Cellular component | cytolytic granule |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | GZMH |
Protein name | Granzyme H Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C) |
Synonyms | CGL2 CTSGL2 |
Description | FUNCTION: Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. . |
Accessions | ENST00000557220.6 ENST00000382548.4 [P20718-2] P20718 ENST00000216338.9 [P20718-1] A0A0C4DGJ9 |