Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| natural killer cell | 18 studies | 23% ± 5% | |
| CD16-positive, CD56-dim natural killer cell, human | 12 studies | 26% ± 7% | |
| CD16-negative, CD56-bright natural killer cell, human | 12 studies | 29% ± 8% | |
| mature NK T cell | 6 studies | 23% ± 6% |
Insufficient scRNA-seq data for expression of NCR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 65.29 | 571 / 578 | 18% | 0.43 | 208 / 1155 |
| spleen | 100% | 276.71 | 241 / 241 | 0% | 0 | 0 / 0 |
| liver | 88% | 21.66 | 198 / 226 | 4% | 0.11 | 16 / 406 |
| peripheral blood | 81% | 310.48 | 757 / 929 | 0% | 0 | 0 / 0 |
| adipose | 68% | 10.93 | 816 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 39% | 4.72 | 35 / 89 | 25% | 0.45 | 226 / 901 |
| uterus | 42% | 4.35 | 71 / 170 | 19% | 0.39 | 88 / 459 |
| breast | 50% | 5.89 | 230 / 459 | 6% | 0.10 | 68 / 1118 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 1.46 | 16 / 29 |
| intestine | 44% | 7.68 | 425 / 966 | 10% | 0.18 | 51 / 527 |
| thymus | 47% | 6.25 | 304 / 653 | 6% | 0.11 | 36 / 605 |
| bladder | 43% | 4.95 | 9 / 21 | 10% | 0.18 | 48 / 504 |
| stomach | 26% | 2.78 | 93 / 359 | 20% | 0.45 | 58 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 38% | 0.91 | 17 / 45 |
| prostate | 34% | 3.87 | 83 / 245 | 0% | 0.00 | 2 / 502 |
| esophagus | 18% | 1.62 | 255 / 1445 | 14% | 0.30 | 25 / 183 |
| blood vessel | 31% | 4.09 | 416 / 1335 | 0% | 0 | 0 / 0 |
| heart | 31% | 3.41 | 264 / 861 | 0% | 0 | 0 / 0 |
| skin | 5% | 0.39 | 87 / 1809 | 22% | 0.59 | 105 / 472 |
| ovary | 22% | 2.19 | 40 / 180 | 3% | 0.05 | 14 / 430 |
| adrenal gland | 10% | 0.88 | 27 / 258 | 1% | 0.02 | 2 / 230 |
| pancreas | 3% | 0.27 | 11 / 328 | 4% | 0.06 | 8 / 178 |
| brain | 8% | 0.64 | 199 / 2642 | 0% | 0.01 | 2 / 705 |
| muscle | 8% | 0.56 | 61 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.04 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0030101 | Biological process | natural killer cell activation |
| GO_0006968 | Biological process | cellular defense response |
| GO_0002764 | Biological process | immune response-regulating signaling pathway |
| GO_0042269 | Biological process | regulation of natural killer cell mediated cytotoxicity |
| GO_0016514 | Cellular component | SWI/SNF complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NCR1 |
| Protein name | Natural cytotoxicity triggering receptor 1 (Lymphocyte antigen 94 homolog) (NK cell-activating receptor) (Natural killer cell p46-related protein) (NK-p46) (NKp46) (hNKp46) (CD antigen CD335) Natural cytotoxicity triggering receptor 1 (Natural killer cell p46-related protein) |
| Synonyms | LY94 |
| Description | FUNCTION: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. . |
| Accessions | ENST00000612896.4 [O76036-1] ENST00000610753.4 [O76036-3] ENST00000614704.4 A0A0G2JNH1 ENST00000611318.4 ENST00000611105.4 [O76036-3] ENST00000616589.4 ENST00000618725.4 ENST00000616780.4 ENST00000610621.4 [O76036-1] ENST00000611942.4 [O76036-2] O76036 ENST00000620296.4 [O76036-2] ENST00000612194.4 ENST00000621652.4 [O76036-4] ENST00000598576.5 A0A0A0MQZ0 ENST00000618585.4 ENST00000613253.1 A0A0A0MR94 ENST00000612645.4 [O76036-3] ENST00000618798.4 ENST00000611233.4 ENST00000615309.1 A0A0G2JMJ3 ENST00000619741.4 ENST00000614280.4 ENST00000617154.4 [O76036-1] ENST00000613135.4 [O76036-5] ENST00000338835.9 ENST00000350790.9 [O76036-3] ENST00000618973.4 [O76036-2] ENST00000619077.4 [O76036-1] ENST00000611098.1 [O76036-5] ENST00000621059.4 [O76036-4] ENST00000291890.9 ENST00000616389.4 ENST00000616747.4 ENST00000357397.5 [O76036-5] ENST00000611120.1 ENST00000619451.1 [O76036-6] ENST00000622620.4 ENST00000594765.5 ENST00000612994.4 ENST00000611122.1 ENST00000620906.4 A0A0A0MTU0 A0A0G2JM39 ENST00000617741.4 A0A0G2JN91 A0A0G2JN63 ENST00000621993.4 ENST00000612239.4 [O76036-6] ENST00000620721.4 M0QYD1 ENST00000613556.1 [O76036-5] ENST00000616564.1 ENST00000622541.1 ENST00000617784.4 [O76036-1] A0A0G2JM44 ENST00000615622.4 [O76036-1] ENST00000611792.4 ENST00000614976.4 |
