CRCP | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	31% ± 15%	Explore
B cell	3 studies	18% ± 1%	Explore

Name	Number of supported studies	Average coverage
peripheral blood	3 studies	18% ± 2%	Explore
brain	3 studies	28% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2036.24	1445 / 1445	100%	37.41	183 / 183
lung	100%	1877.82	578 / 578	100%	41.87	1155 / 1155
ovary	100%	1994.46	180 / 180	100%	28.44	430 / 430
pancreas	100%	1349.04	328 / 328	100%	34.63	178 / 178
prostate	100%	2286.58	245 / 245	100%	45.78	502 / 502
stomach	100%	1787.41	359 / 359	100%	38.56	286 / 286
uterus	100%	1974.08	170 / 170	100%	37.19	459 / 459
brain	100%	1972.75	2641 / 2642	100%	51.56	705 / 705
breast	100%	2045.65	459 / 459	100%	50.10	1117 / 1118
intestine	100%	2114.12	966 / 966	100%	41.79	526 / 527
bladder	100%	2259.62	21 / 21	100%	40.73	503 / 504
liver	100%	2678.24	226 / 226	100%	27.28	405 / 406
thymus	100%	1914.23	653 / 653	100%	37.48	603 / 605
kidney	100%	1774.79	89 / 89	100%	30.92	897 / 901
adrenal gland	100%	2207.48	258 / 258	99%	42.10	228 / 230
skin	100%	2307.34	1809 / 1809	98%	33.79	464 / 472
adipose	100%	1953.57	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1974.35	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	30.53	29 / 29
spleen	100%	2096.61	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	31.50	45 / 45
ureter	0%	0	0 / 0	100%	24.87	1 / 1
muscle	100%	1000.00	801 / 803	0%	0	0 / 0
heart	98%	1242.49	843 / 861	0%	0	0 / 0
peripheral blood	96%	1434.79	894 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	89%	15.53	71 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006384	Biological process	transcription initiation at RNA polymerase III promoter
GO_0045087	Biological process	innate immune response
GO_0051607	Biological process	defense response to virus
GO_0007218	Biological process	neuropeptide signaling pathway
GO_0006383	Biological process	transcription by RNA polymerase III
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0001669	Cellular component	acrosomal vesicle
GO_0005666	Cellular component	RNA polymerase III complex
GO_0005886	Cellular component	plasma membrane
GO_0009360	Cellular component	DNA polymerase III complex
GO_0001635	Molecular function	calcitonin gene-related peptide receptor activity
GO_0005515	Molecular function	protein binding
GO_0000166	Molecular function	nucleotide binding
GO_0003899	Molecular function	DNA-directed 5'-3' RNA polymerase activity

Gene name	CRCP
Protein name	DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9) (Calcitonin gene-related peptide-receptor component protein) (CGRP-RCP) (CGRP-receptor component protein) (CGRPRCP) (HsC17) CGRP receptor component
Synonyms
Description	FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates . Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With POLR3H/RPC8 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation (By similarity). Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway . .; FUNCTION: Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues. .
Accessions	ENST00000338592.5 [O75575-2] ENST00000395326.8 [O75575-1] H7BY40 ENST00000360415.7 O75575 ENST00000398684.6 [O75575-4] ENST00000431089.6 [O75575-3]

CRCP report