Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 9 studies | 32% ± 13% | |
| glutamatergic neuron | 5 studies | 41% ± 20% | |
| astrocyte | 5 studies | 25% ± 9% | |
| neuron | 4 studies | 20% ± 3% | |
| GABAergic neuron | 3 studies | 45% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 30% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 7262.68 | 2627 / 2642 | 97% | 76.50 | 685 / 705 |
| adrenal gland | 45% | 469.10 | 115 / 258 | 61% | 13.90 | 140 / 230 |
| skin | 55% | 814.81 | 986 / 1809 | 41% | 8.93 | 195 / 472 |
| spleen | 91% | 880.10 | 219 / 241 | 0% | 0 | 0 / 0 |
| ovary | 48% | 326.63 | 86 / 180 | 32% | 4.06 | 136 / 430 |
| uterus | 55% | 512.55 | 93 / 170 | 15% | 1.33 | 67 / 459 |
| eye | 0% | 0 | 0 / 0 | 66% | 6.50 | 53 / 80 |
| prostate | 53% | 428.36 | 130 / 245 | 10% | 0.58 | 52 / 502 |
| lung | 16% | 98.26 | 90 / 578 | 25% | 4.16 | 288 / 1155 |
| esophagus | 6% | 39.13 | 91 / 1445 | 24% | 4.44 | 44 / 183 |
| breast | 12% | 84.76 | 53 / 459 | 16% | 0.87 | 177 / 1118 |
| intestine | 20% | 135.62 | 198 / 966 | 2% | 0.10 | 9 / 527 |
| thymus | 6% | 33.99 | 38 / 653 | 13% | 1.75 | 78 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 0.73 | 5 / 29 |
| kidney | 7% | 36.56 | 6 / 89 | 10% | 1.97 | 88 / 901 |
| pancreas | 0% | 1.45 | 1 / 328 | 16% | 0.67 | 28 / 178 |
| stomach | 11% | 76.69 | 41 / 359 | 5% | 0.18 | 13 / 286 |
| blood vessel | 8% | 51.04 | 109 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.93 | 3 / 45 |
| liver | 0% | 0 | 0 / 226 | 5% | 0.25 | 22 / 406 |
| adipose | 5% | 27.92 | 58 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 4% | 0.43 | 22 / 504 |
| peripheral blood | 1% | 6.22 | 7 / 929 | 0% | 0 | 0 / 0 |
| heart | 1% | 3.64 | 6 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042177 | Biological process | negative regulation of protein catabolic process |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0045087 | Biological process | innate immune response |
| GO_0050829 | Biological process | defense response to Gram-negative bacterium |
| GO_0007165 | Biological process | signal transduction |
| GO_1903428 | Biological process | positive regulation of reactive oxygen species biosynthetic process |
| GO_0007155 | Biological process | cell adhesion |
| GO_1901741 | Biological process | positive regulation of myoblast fusion |
| GO_0007409 | Biological process | axonogenesis |
| GO_0016525 | Biological process | negative regulation of angiogenesis |
| GO_0043277 | Biological process | apoptotic cell clearance |
| GO_0048167 | Biological process | regulation of synaptic plasticity |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0006910 | Biological process | phagocytosis, recognition |
| GO_0007422 | Biological process | peripheral nervous system development |
| GO_0007517 | Biological process | muscle organ development |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0010596 | Biological process | negative regulation of endothelial cell migration |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0043652 | Biological process | engulfment of apoptotic cell |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0031397 | Biological process | negative regulation of protein ubiquitination |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043197 | Cellular component | dendritic spine |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0030425 | Cellular component | dendrite |
| GO_0001891 | Cellular component | phagocytic cup |
| GO_0014069 | Cellular component | postsynaptic density |
| GO_0004930 | Molecular function | G protein-coupled receptor activity |
| GO_0001786 | Molecular function | phosphatidylserine binding |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0001530 | Molecular function | lipopolysaccharide binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ADGRB1 |
| Protein name | Adhesion G protein-coupled receptor B1 (Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-40 (Vstat40); Vasculostatin-120 (Vstat120)] Adhesion G protein-coupled receptor B1 |
| Synonyms | BAI1 |
| Description | FUNCTION: Phosphatidylserine receptor which enhances the engulfment of apoptotic cells . Also mediates the binding and engulfment of Gram-negative bacteria . Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity . In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells . Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner . Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity). Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity). Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma . .; FUNCTION: [Vasculostatin-120]: Inhibits angiogenesis in a CD36-dependent manner. .; FUNCTION: [Vasculostatin-40]: Inhibits angiogenesis. . |
| Accessions | ENST00000521208.5 ENST00000643448.1 A0A2R8Y5M7 ENST00000517894.6 O14514 E5RG74 |
