Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 46 studies | 63% ± 24% | |
smooth muscle cell | 23 studies | 26% ± 10% | |
pericyte | 22 studies | 32% ± 17% | |
connective tissue cell | 17 studies | 54% ± 22% | |
myofibroblast cell | 14 studies | 47% ± 23% | |
mesothelial cell | 12 studies | 48% ± 23% | |
hepatocyte | 6 studies | 66% ± 24% | |
endothelial cell | 6 studies | 28% ± 10% | |
adipocyte | 6 studies | 29% ± 10% | |
astrocyte | 5 studies | 24% ± 8% | |
adventitial cell | 5 studies | 80% ± 20% | |
Schwann cell | 4 studies | 36% ± 14% | |
hepatic stellate cell | 3 studies | 49% ± 16% | |
T cell | 3 studies | 18% ± 2% | |
epithelial cell | 3 studies | 26% ± 14% | |
abnormal cell | 3 studies | 43% ± 21% | |
muscle cell | 3 studies | 39% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 103099.42 | 226 / 226 | 99% | 738.55 | 402 / 406 |
lung | 100% | 40571.42 | 576 / 578 | 95% | 199.26 | 1101 / 1155 |
breast | 99% | 51348.84 | 456 / 459 | 92% | 197.20 | 1024 / 1118 |
ovary | 100% | 83836.28 | 180 / 180 | 80% | 100.27 | 344 / 430 |
prostate | 93% | 24061.42 | 228 / 245 | 84% | 96.70 | 424 / 502 |
bladder | 100% | 49672.10 | 21 / 21 | 74% | 122.71 | 374 / 504 |
intestine | 99% | 34459.76 | 954 / 966 | 75% | 102.44 | 394 / 527 |
uterus | 100% | 40037.42 | 170 / 170 | 73% | 115.77 | 335 / 459 |
esophagus | 93% | 34963.57 | 1339 / 1445 | 78% | 118.11 | 142 / 183 |
stomach | 82% | 25408.14 | 295 / 359 | 79% | 105.58 | 225 / 286 |
skin | 85% | 20382.51 | 1545 / 1809 | 72% | 102.54 | 339 / 472 |
thymus | 99% | 29488.81 | 644 / 653 | 42% | 47.05 | 254 / 605 |
pancreas | 35% | 3754.42 | 115 / 328 | 90% | 281.54 | 161 / 178 |
kidney | 53% | 11436.62 | 47 / 89 | 72% | 145.11 | 653 / 901 |
adrenal gland | 90% | 20975.03 | 233 / 258 | 29% | 27.53 | 67 / 230 |
adipose | 100% | 65052.63 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 147.50 | 29 / 29 |
ureter | 0% | 0 | 0 / 0 | 100% | 46.96 | 1 / 1 |
blood vessel | 100% | 46145.33 | 1333 / 1335 | 0% | 0 | 0 / 0 |
spleen | 99% | 25074.29 | 238 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 126.15 | 40 / 45 |
heart | 75% | 17497.14 | 645 / 861 | 0% | 0 | 0 / 0 |
brain | 2% | 169.14 | 40 / 2642 | 43% | 55.41 | 301 / 705 |
muscle | 39% | 4318.99 | 312 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 12.00 | 12 / 80 |
peripheral blood | 0% | 8.58 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006958 | Biological process | complement activation, classical pathway |
GO_0006508 | Biological process | proteolysis |
GO_0045087 | Biological process | innate immune response |
GO_0005615 | Cellular component | extracellular space |
GO_0072562 | Cellular component | blood microparticle |
GO_0005576 | Cellular component | extracellular region |
GO_0005509 | Molecular function | calcium ion binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | C1S |
Protein name | Complement C1s Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain] |
Synonyms | |
Description | FUNCTION: C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. |
Accessions | ENST00000328916.7 ENST00000360817.10 F8WCZ6 ENST00000423384.5 H0Y5D1 F5H7T4 ENST00000443875.5 ENST00000542978.1 ENST00000406697.5 C9JY52 B5MCV4 ENST00000403949.5 ENST00000402681.7 P09871 ENST00000413211.5 C9IZP8 |