C1S report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006958Biological processcomplement activation, classical pathway
GO_0006508Biological processproteolysis
GO_0045087Biological processinnate immune response
GO_0005615Cellular componentextracellular space
GO_0072562Cellular componentblood microparticle
GO_0005576Cellular componentextracellular region
GO_0005509Molecular functioncalcium ion binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameC1S
Protein nameComplement C1s
Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain]
Synonyms
DescriptionFUNCTION: C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

AccessionsENST00000328916.7
ENST00000360817.10
F8WCZ6
ENST00000423384.5
H0Y5D1
F5H7T4
ENST00000443875.5
ENST00000542978.1
ENST00000406697.5
C9JY52
B5MCV4
ENST00000403949.5
ENST00000402681.7
P09871
ENST00000413211.5
C9IZP8