Insufficient scRNA-seq data for expression of TREML4 at single-cell level.
Insufficient scRNA-seq data for expression of TREML4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 94% | 43.71 | 546 / 578 | 8% | 0.21 | 88 / 1155 |
| spleen | 92% | 65.44 | 222 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 82% | 214.53 | 761 / 929 | 0% | 0 | 0 / 0 |
| adipose | 46% | 8.90 | 550 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 27% | 2.85 | 97 / 359 | 1% | 0.08 | 4 / 286 |
| blood vessel | 25% | 3.50 | 339 / 1335 | 0% | 0 | 0 / 0 |
| breast | 22% | 2.32 | 101 / 459 | 1% | 0.01 | 8 / 1118 |
| liver | 19% | 2.08 | 43 / 226 | 2% | 0.07 | 9 / 406 |
| adrenal gland | 21% | 2.43 | 54 / 258 | 0% | 0 | 0 / 230 |
| heart | 21% | 2.18 | 180 / 861 | 0% | 0 | 0 / 0 |
| intestine | 17% | 2.20 | 164 / 966 | 1% | 0.02 | 7 / 527 |
| bladder | 14% | 2.81 | 3 / 21 | 3% | 0.08 | 13 / 504 |
| prostate | 16% | 1.72 | 40 / 245 | 0% | 0 | 0 / 502 |
| thymus | 13% | 1.16 | 84 / 653 | 1% | 0.01 | 5 / 605 |
| brain | 11% | 1.37 | 279 / 2642 | 3% | 0.04 | 18 / 705 |
| uterus | 12% | 1.51 | 20 / 170 | 0% | 0.01 | 2 / 459 |
| kidney | 11% | 1.38 | 10 / 89 | 1% | 0.01 | 6 / 901 |
| esophagus | 9% | 0.96 | 131 / 1445 | 3% | 0.04 | 5 / 183 |
| pancreas | 8% | 0.84 | 26 / 328 | 1% | 0.01 | 1 / 178 |
| ovary | 8% | 0.66 | 14 / 180 | 0% | 0 | 0 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.16 | 2 / 29 |
| muscle | 3% | 0.16 | 21 / 803 | 0% | 0 | 0 / 0 |
| skin | 2% | 0.15 | 34 / 1809 | 0% | 0.01 | 2 / 472 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034157 | Biological process | positive regulation of toll-like receptor 7 signaling pathway |
| GO_0045087 | Biological process | innate immune response |
| GO_0009986 | Cellular component | cell surface |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0038023 | Molecular function | signaling receptor activity |
| Gene name | TREML4 |
| Protein name | Trem-like transcript 4 protein (TLT-4) (Triggering receptor expressed on myeloid cells-like protein 4) Triggering receptor expressed on myeloid cells like 4 |
| Synonyms | TLT4 UNQ9425/PRO34675 |
| Description | FUNCTION: Positively regulates Toll-like receptor TLR7 signaling in macrophages. . |
| Accessions | ENST00000461240.1 ENST00000341495.7 ENST00000448827.6 H7C4X5 Q6UXN2 |