TARM1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TARM1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TARM1 at tissue level.

III. Associated gene sets

GO_0002250Biological processadaptive immune response
GO_2000515Biological processnegative regulation of CD4-positive, alpha-beta T cell activation
GO_0002764Biological processimmune response-regulating signaling pathway
GO_0045087Biological processinnate immune response
GO_0070821Cellular componenttertiary granule membrane
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0034987Molecular functionimmunoglobulin receptor binding

IV. Literature review

[source]
Gene nameTARM1
Protein nameT cell-interacting, activating receptor on myeloid cells 1
T-cell-interacting, activating receptor on myeloid cells protein 1 (OSCAR-like transcript-2 protein) (OLT-2)
Synonyms
DescriptionFUNCTION: May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface . Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity). .

AccessionsENST00000620398.1
ENST00000615726.1
B6A8C7
A0A087X1Q6
ENST00000616041.4
ENST00000611419.1
ENST00000611088.1
ENST00000612678.1
ENST00000432826.2 [B6A8C7-1]
ENST00000620140.4
ENST00000620707.1
ENST00000616041.4 [B6A8C7-2]
ENST00000622245.1
ENST00000619320.1
ENST00000614463.1