TRIM4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0010468Biological processregulation of gene expression
GO_0045087Biological processinnate immune response
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0042802Molecular functionidentical protein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTRIM4
Protein nameTripartite motif containing 4
E3 ubiquitin-protein ligase TRIM4 (EC 2.3.2.27) (RING finger protein 87) (RING-type E3 ubiquitin transferase TRIM4) (Tripartite motif-containing protein 4)
SynonymsRNF87
DescriptionFUNCTION: E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction. .

AccessionsENST00000447480.5
H7C0Q6
ENST00000355947.6 [Q9C037-1]
Q9C037
ENST00000354241.5 [Q9C037-3]
ENST00000349062.7 [Q9C037-2]