Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 21% ± 5% | |
| epithelial cell | 4 studies | 27% ± 4% | |
| astrocyte | 4 studies | 25% ± 6% | |
| GABAergic neuron | 3 studies | 32% ± 3% | |
| glutamatergic neuron | 3 studies | 39% ± 5% | |
| oligodendrocyte | 3 studies | 20% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2667.82 | 245 / 245 | 100% | 34.63 | 501 / 502 |
| breast | 100% | 3222.85 | 459 / 459 | 100% | 40.75 | 1115 / 1118 |
| intestine | 100% | 2335.17 | 966 / 966 | 100% | 28.06 | 525 / 527 |
| stomach | 100% | 2070.53 | 359 / 359 | 99% | 25.22 | 284 / 286 |
| lung | 100% | 2214.95 | 576 / 578 | 100% | 26.01 | 1150 / 1155 |
| thymus | 100% | 2795.21 | 653 / 653 | 99% | 34.78 | 600 / 605 |
| esophagus | 100% | 2102.87 | 1445 / 1445 | 99% | 24.25 | 181 / 183 |
| pancreas | 100% | 1756.34 | 327 / 328 | 99% | 27.36 | 176 / 178 |
| adrenal gland | 100% | 3080.83 | 258 / 258 | 98% | 35.23 | 226 / 230 |
| brain | 98% | 1077.88 | 2593 / 2642 | 100% | 35.62 | 704 / 705 |
| kidney | 100% | 1733.71 | 89 / 89 | 98% | 32.17 | 882 / 901 |
| bladder | 100% | 2653.81 | 21 / 21 | 97% | 22.39 | 490 / 504 |
| skin | 100% | 3010.94 | 1809 / 1809 | 97% | 41.58 | 457 / 472 |
| uterus | 100% | 3071.98 | 170 / 170 | 95% | 19.66 | 435 / 459 |
| liver | 100% | 1375.93 | 226 / 226 | 94% | 17.98 | 382 / 406 |
| ovary | 100% | 3839.66 | 180 / 180 | 86% | 14.76 | 371 / 430 |
| adipose | 100% | 2848.83 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2890.44 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 25.30 | 29 / 29 |
| spleen | 100% | 2506.59 | 241 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 33.38 | 78 / 80 |
| heart | 97% | 938.50 | 836 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 21.21 | 43 / 45 |
| muscle | 87% | 660.82 | 697 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 80% | 1139.93 | 740 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0010468 | Biological process | regulation of gene expression |
| GO_0045087 | Biological process | innate immune response |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0061630 | Molecular function | ubiquitin protein ligase activity |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | TRIM4 |
| Protein name | Tripartite motif containing 4 E3 ubiquitin-protein ligase TRIM4 (EC 2.3.2.27) (RING finger protein 87) (RING-type E3 ubiquitin transferase TRIM4) (Tripartite motif-containing protein 4) |
| Synonyms | RNF87 |
| Description | FUNCTION: E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor RIGI, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction. . |
| Accessions | ENST00000447480.5 H7C0Q6 ENST00000355947.6 [Q9C037-1] Q9C037 ENST00000354241.5 [Q9C037-3] ENST00000349062.7 [Q9C037-2] |