Name | Number of supported studies | Average coverage | |
---|---|---|---|
basal cell | 19 studies | 58% ± 25% | |
ciliated cell | 18 studies | 75% ± 19% | |
epithelial cell | 16 studies | 67% ± 27% | |
club cell | 11 studies | 75% ± 32% | |
secretory cell | 11 studies | 88% ± 10% | |
type II pneumocyte | 10 studies | 74% ± 31% | |
mesothelial cell | 10 studies | 58% ± 28% | |
respiratory goblet cell | 8 studies | 78% ± 28% | |
type I pneumocyte | 7 studies | 52% ± 17% | |
ionocyte | 7 studies | 48% ± 27% | |
endothelial cell of lymphatic vessel | 6 studies | 32% ± 25% | |
fibroblast | 6 studies | 40% ± 23% | |
mucus secreting cell | 6 studies | 56% ± 23% | |
abnormal cell | 5 studies | 42% ± 21% | |
deuterosomal cell | 4 studies | 84% ± 6% | |
duct epithelial cell | 4 studies | 99% ± 1% | |
squamous epithelial cell | 4 studies | 79% ± 12% | |
kidney loop of Henle epithelial cell | 4 studies | 30% ± 10% | |
adventitial cell | 4 studies | 51% ± 12% | |
endothelial cell of artery | 4 studies | 24% ± 5% | |
vein endothelial cell | 4 studies | 23% ± 2% | |
T cell | 3 studies | 44% ± 29% | |
endothelial cell | 3 studies | 39% ± 32% | |
hillock cell | 3 studies | 64% ± 34% | |
neutrophil | 3 studies | 27% ± 9% | |
CD8-positive, alpha-beta T cell | 3 studies | 27% ± 7% | |
serous secreting cell | 3 studies | 92% ± 10% | |
keratinocyte | 3 studies | 29% ± 13% | |
progenitor cell of mammary luminal epithelium | 3 studies | 50% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 96% | 19721.58 | 553 / 578 | 75% | 1629.69 | 871 / 1155 |
esophagus | 79% | 10239.08 | 1140 / 1445 | 72% | 915.67 | 132 / 183 |
liver | 89% | 2969.33 | 202 / 226 | 54% | 591.62 | 221 / 406 |
bladder | 90% | 5226.48 | 19 / 21 | 43% | 779.55 | 215 / 504 |
ovary | 7% | 117.27 | 13 / 180 | 96% | 4506.73 | 412 / 430 |
stomach | 60% | 1362.42 | 217 / 359 | 40% | 288.40 | 113 / 286 |
pancreas | 15% | 221.79 | 49 / 328 | 79% | 1056.99 | 141 / 178 |
uterus | 12% | 2812.21 | 20 / 170 | 75% | 3327.54 | 346 / 459 |
breast | 62% | 2336.83 | 286 / 459 | 22% | 378.02 | 247 / 1118 |
kidney | 61% | 4701.87 | 54 / 89 | 21% | 557.57 | 189 / 901 |
tonsil | 0% | 0 | 0 / 0 | 80% | 1229.57 | 36 / 45 |
skin | 72% | 3732.11 | 1303 / 1809 | 7% | 82.84 | 31 / 472 |
intestine | 27% | 484.39 | 260 / 966 | 47% | 383.72 | 246 / 527 |
muscle | 70% | 8040.05 | 559 / 803 | 0% | 0 | 0 / 0 |
prostate | 55% | 2202.18 | 135 / 245 | 12% | 106.80 | 58 / 502 |
thymus | 21% | 380.56 | 140 / 653 | 44% | 648.87 | 266 / 605 |
peripheral blood | 62% | 2904.02 | 580 / 929 | 0% | 0 | 0 / 0 |
adipose | 44% | 2446.63 | 534 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 32% | 659.04 | 433 / 1335 | 0% | 0 | 0 / 0 |
spleen | 13% | 217.64 | 32 / 241 | 0% | 0 | 0 / 0 |
heart | 9% | 486.79 | 81 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 2% | 236.08 | 5 / 258 | 7% | 393.51 | 16 / 230 |
brain | 0% | 15.27 | 13 / 2642 | 4% | 25.35 | 27 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0045071 | Biological process | negative regulation of viral genome replication |
GO_0045087 | Biological process | innate immune response |
GO_0019731 | Biological process | antibacterial humoral response |
GO_0006955 | Biological process | immune response |
GO_0035821 | Biological process | modulation of process of another organism |
GO_0032091 | Biological process | negative regulation of protein binding |
GO_0032496 | Biological process | response to lipopolysaccharide |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0035580 | Cellular component | specific granule lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0003677 | Molecular function | DNA binding |
GO_0019899 | Molecular function | enzyme binding |
GO_0004866 | Molecular function | endopeptidase inhibitor activity |
GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
GO_0003729 | Molecular function | mRNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SLPI |
Protein name | Secretory leukoprotease inhibitor protein Antileukoproteinase (ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4) |
Synonyms | WAP4 WFDC4 |
Description | FUNCTION: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G . Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS) (By similarity). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses . Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance to infection by L.major. Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (By similarity). Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells . . |
Accessions | P03973 Q6LDI0 ENST00000338380.2 |