Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 23% ± 7% | |
| capillary endothelial cell | 7 studies | 19% ± 4% | |
| respiratory goblet cell | 4 studies | 21% ± 5% | |
| epithelial cell | 3 studies | 39% ± 13% | |
| fibroblast | 3 studies | 28% ± 10% |
Insufficient scRNA-seq data for expression of APOL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 9783.00 | 226 / 226 | 94% | 166.43 | 380 / 406 |
| kidney | 100% | 4812.48 | 89 / 89 | 93% | 291.95 | 836 / 901 |
| lung | 100% | 8202.60 | 578 / 578 | 93% | 246.33 | 1071 / 1155 |
| bladder | 100% | 6760.38 | 21 / 21 | 90% | 365.33 | 452 / 504 |
| uterus | 100% | 4271.00 | 170 / 170 | 88% | 459.65 | 406 / 459 |
| esophagus | 99% | 3455.59 | 1435 / 1445 | 84% | 129.11 | 154 / 183 |
| intestine | 100% | 3951.41 | 966 / 966 | 81% | 135.72 | 427 / 527 |
| breast | 100% | 4053.27 | 459 / 459 | 79% | 89.05 | 888 / 1118 |
| thymus | 99% | 2655.21 | 647 / 653 | 79% | 78.47 | 476 / 605 |
| stomach | 94% | 3391.19 | 339 / 359 | 80% | 121.98 | 230 / 286 |
| ovary | 100% | 3029.44 | 180 / 180 | 73% | 105.09 | 313 / 430 |
| prostate | 100% | 5377.00 | 245 / 245 | 69% | 59.39 | 345 / 502 |
| pancreas | 40% | 446.00 | 130 / 328 | 96% | 372.34 | 170 / 178 |
| skin | 62% | 759.28 | 1126 / 1809 | 63% | 101.73 | 295 / 472 |
| adrenal gland | 98% | 2139.98 | 254 / 258 | 25% | 21.69 | 58 / 230 |
| adipose | 100% | 4636.83 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5984.98 | 241 / 241 | 0% | 0 | 0 / 0 |
| heart | 99% | 2082.89 | 850 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 572.05 | 44 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 158.26 | 28 / 29 |
| blood vessel | 93% | 2399.84 | 1235 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 76% | 2321.24 | 707 / 929 | 0% | 0 | 0 / 0 |
| muscle | 41% | 389.72 | 333 / 803 | 0% | 0 | 0 / 0 |
| brain | 26% | 329.08 | 689 / 2642 | 11% | 10.94 | 79 / 705 |
| eye | 0% | 0 | 0 / 0 | 18% | 36.29 | 14 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008203 | Biological process | cholesterol metabolic process |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0051838 | Biological process | cytolysis by host of symbiont cells |
| GO_0042157 | Biological process | lipoprotein metabolic process |
| GO_0006869 | Biological process | lipid transport |
| GO_0045087 | Biological process | innate immune response |
| GO_0005615 | Cellular component | extracellular space |
| GO_0034364 | Cellular component | high-density lipoprotein particle |
| GO_0072562 | Cellular component | blood microparticle |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0034361 | Cellular component | very-low-density lipoprotein particle |
| GO_0005254 | Molecular function | chloride channel activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008289 | Molecular function | lipid binding |
| Gene name | APOL1 |
| Protein name | Apolipoprotein L1-B3 APOL1 protein (Apolipoprotein L, 1) Apolipoprotein L 1 isoform 2 APOL1 protein Apolipoprotein L1 (Apolipoprotein L) (Apo-L) (ApoL) (Apolipoprotein L-I) (ApoL-I) Apolipoprotein L1 Apolipoprotein L 1 isoform 1 Alternative protein APOL1 Apolipoprotein L1 (cDNA FLJ59906, moderately similar to Apolipoprotein-L1) |
| Synonyms | APOL |
| Description | FUNCTION: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
| Accessions | A0A1B2FJD8 A0A1B2FK87 ENST00000426053.5 [O14791-3] A5PL32 A0A1B2FK30 A0A1B2FJU3 A0A1B2FJU6 A0A1B2FIW3 A0A1B2FJA9 U5LKN0 A0A1B2FIW1 A0A1B2FK76 ENST00000433768.6 A0A1B2FJQ0 U5LKR8 A0A1B2FK65 A0A1B2FJ57 A0A1B2FJX9 U5LIG7 U5LGY0 A0A1B2FJD2 A0A1B2FJS1 A0A1B2FJT3 ENST00000319136.8 [O14791-2] U5LKT7 A0A1B2FK99 A0A1B2FK47 A0A1B2FJT7 A0A1B2FK36 Q1WWL5 A0A1B2FJZ7 A0A1B2FJJ6 A0A1B2FIV9 A0A1B2FJK6 A0A1B2FJD3 A0A1B2FJA7 A0A1B2FK85 A0A1B2FJ29 A0A1B2FIX3 A0A1B2FJB2 A0A1B2FJT1 U5LKN4 A0A1B2FJP1 A0A1B2FJ89 A0A1B2FJW8 A0A1B2FIX0 B1AH95 A0A1B2FJR5 Q29RW7 ENST00000427990.6 [O14791-1] A0A1B2FJW9 A0A1B2FJE5 A0A1B2FJF3 A0A1B2FJU4 U5LI90 A0A1B2FJI3 Q2KHQ6 A0A1B2FJS0 U5LGU2 L8ECA5 A0A1B2FJ64 A0A1B2FK27 A0A1B2FJ82 A0A1B2FJ32 U5LII8 A0A1B2FJK3 U5LKH9 U5LKG0 A0A1B2FJC1 A0A1B2FJR1 A0A0S2Z4X6 A0A1B2FKD8 A0A1B2FKD5 ENST00000427990.5 A0A1B2FJ11 B1AH96 A0A1B2FJS4 A0A1B2FJF7 B1AH94 U5LIC5 A0A1B2FJV6 O14791 U5LIJ1 U5LH46 A0A1B2FK07 A0A1B2FK72 A0A1P8SD62 A0A1B2FK26 U5LKQ0 A0A1B2FJ21 A0A1B2FIY0 A0A1B2FIW9 A0A1B2FJI7 U5LIA9 A0A1B2FJ38 ENST00000438034.6 U5LKJ0 U5LIH6 A0A1B2FJH1 U5LKC6 A0A1B2FJB1 A0A1B2FJJ4 A0A1B2FK40 U5LHF6 U5LH96 U5LGW0 U5LKP5 ENST00000397278.8 [O14791-1] A0A0S2Z4M8 U5LKM6 |
