Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 18 studies | 44% ± 23% | |
| non-classical monocyte | 10 studies | 21% ± 6% | |
| alveolar macrophage | 8 studies | 75% ± 19% | |
| classical monocyte | 8 studies | 25% ± 6% | |
| monocyte | 5 studies | 30% ± 18% | |
| myeloid cell | 3 studies | 26% ± 8% | |
| dendritic cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 5 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 7618.94 | 577 / 578 | 78% | 61.57 | 900 / 1155 |
| bladder | 57% | 534.52 | 12 / 21 | 36% | 18.13 | 183 / 504 |
| ovary | 52% | 324.88 | 93 / 180 | 41% | 7.42 | 178 / 430 |
| adipose | 90% | 2234.53 | 1082 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 90% | 3433.78 | 216 / 241 | 0% | 0 | 0 / 0 |
| breast | 60% | 708.95 | 274 / 459 | 30% | 10.16 | 333 / 1118 |
| adrenal gland | 79% | 1081.26 | 203 / 258 | 9% | 3.30 | 21 / 230 |
| liver | 62% | 1354.94 | 141 / 226 | 19% | 4.71 | 78 / 406 |
| pancreas | 6% | 32.14 | 19 / 328 | 75% | 39.60 | 133 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 98.82 | 23 / 29 |
| thymus | 19% | 134.97 | 125 / 653 | 60% | 18.33 | 363 / 605 |
| skin | 25% | 129.20 | 445 / 1809 | 53% | 24.64 | 251 / 472 |
| intestine | 47% | 446.04 | 451 / 966 | 30% | 9.29 | 159 / 527 |
| peripheral blood | 76% | 1311.46 | 703 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 41% | 422.25 | 597 / 1445 | 25% | 4.52 | 45 / 183 |
| heart | 54% | 859.36 | 465 / 861 | 0% | 0 | 0 / 0 |
| stomach | 27% | 303.97 | 97 / 359 | 25% | 5.14 | 71 / 286 |
| uterus | 12% | 142.99 | 21 / 170 | 39% | 11.60 | 178 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 16.54 | 23 / 45 |
| kidney | 10% | 135.48 | 9 / 89 | 36% | 8.64 | 325 / 901 |
| blood vessel | 36% | 400.31 | 480 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 24% | 156.43 | 58 / 245 | 5% | 0.51 | 26 / 502 |
| brain | 5% | 16.79 | 119 / 2642 | 14% | 5.40 | 102 / 705 |
| eye | 0% | 0 | 0 / 0 | 11% | 1.74 | 9 / 80 |
| muscle | 11% | 50.94 | 87 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006898 | Biological process | receptor-mediated endocytosis |
| GO_0045087 | Biological process | innate immune response |
| GO_0001934 | Biological process | positive regulation of protein phosphorylation |
| GO_0006911 | Biological process | phagocytosis, engulfment |
| GO_0097242 | Biological process | amyloid-beta clearance |
| GO_0043277 | Biological process | apoptotic cell clearance |
| GO_0007193 | Biological process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0005581 | Cellular component | collagen trimer |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0038187 | Molecular function | pattern recognition receptor activity |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0038024 | Molecular function | cargo receptor activity |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0001664 | Molecular function | G protein-coupled receptor binding |
| Gene name | MARCO |
| Protein name | Macrophage receptor with collagenous structure Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2) Macrophage receptor |
| Synonyms | hCG_16205 SCARA2 |
| Description | FUNCTION: Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria . Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 . . |
| Accessions | C9JKT8 Q9UEW3 A0A1S5UZ24 ENST00000412481.1 ENST00000327097.5 [Q9UEW3-1] Q4ZG40 |
