CRP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006953Biological processacute-phase response
GO_0006954Biological processinflammatory response
GO_0045087Biological processinnate immune response
GO_0010628Biological processpositive regulation of gene expression
GO_0032677Biological processregulation of interleukin-8 production
GO_0010745Biological processnegative regulation of macrophage derived foam cell differentiation
GO_0050830Biological processdefense response to Gram-positive bacterium
GO_0008228Biological processopsonization
GO_0032930Biological processpositive regulation of superoxide anion generation
GO_0010888Biological processnegative regulation of lipid storage
GO_0042310Biological processvasoconstriction
GO_0032945Biological processnegative regulation of mononuclear cell proliferation
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0033265Molecular functioncholine binding
GO_0042802Molecular functionidentical protein binding
GO_0050750Molecular functionlow-density lipoprotein particle receptor binding
GO_0030169Molecular functionlow-density lipoprotein particle binding
GO_0001849Molecular functioncomplement component C1q complex binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0046790Molecular functionvirion binding

IV. Literature review

[source]
Gene nameCRP
Protein nameC-reactive protein
C-reactive protein [Cleaved into: C-reactive protein(1-205)]
SynonymsPTX1
DescriptionFUNCTION: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

FUNCTION: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. .

FUNCTION: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. .

AccessionsENST00000368112.5 [P02741-2]
C9JRE9
ENST00000437342.1
ENST00000368110.1
ENST00000255030.9 [P02741-1]
P02741
ENST00000368111.5
Q5VVP7