BPIFC report

I. Expression across cell types

Insufficient scRNA-seq data for expression of BPIFC at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BPIFC at tissue level.

III. Associated gene sets

GO_0045087Biological processinnate immune response
GO_0005615Cellular componentextracellular space
GO_0005543Molecular functionphospholipid binding
GO_0001530Molecular functionlipopolysaccharide binding

IV. Literature review

[source]
Gene nameBPIFC
Protein nameBPI fold containing family C
Bactericidal permeability-increasing protein (BPI)
BPI fold-containing family C protein (Bactericidal/permeability-increasing protein-like 2) (BPI-like 2)
SynonymsBPIL2
DescriptionFUNCTION: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. .

AccessionsENST00000397450.2
Q5TI88
ENST00000300399.9 [Q8NFQ6-1]
A0A8C8NLL8
Q8NFQ6
ENST00000397452.5 [Q8NFQ6-1]
ENST00000534972.4