Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 45 studies | 68% ± 23% | |
microglial cell | 14 studies | 54% ± 28% | |
conventional dendritic cell | 11 studies | 38% ± 11% | |
myeloid cell | 10 studies | 55% ± 25% | |
non-classical monocyte | 10 studies | 26% ± 12% | |
alveolar macrophage | 8 studies | 64% ± 29% | |
mononuclear phagocyte | 8 studies | 39% ± 21% | |
monocyte | 8 studies | 45% ± 20% | |
leukocyte | 7 studies | 38% ± 10% | |
dendritic cell | 6 studies | 42% ± 29% | |
classical monocyte | 3 studies | 36% ± 15% | |
tissue-resident macrophage | 3 studies | 72% ± 20% | |
monocyte-derived dendritic cell | 3 studies | 35% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 5 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 97% | 10352.22 | 562 / 578 | 90% | 430.87 | 1036 / 1155 |
breast | 89% | 3594.32 | 409 / 459 | 90% | 285.47 | 1011 / 1118 |
intestine | 92% | 4581.69 | 886 / 966 | 75% | 235.66 | 394 / 527 |
bladder | 95% | 3090.52 | 20 / 21 | 65% | 284.28 | 329 / 504 |
adrenal gland | 95% | 7969.13 | 246 / 258 | 60% | 176.98 | 138 / 230 |
stomach | 75% | 2171.97 | 268 / 359 | 80% | 304.86 | 229 / 286 |
ovary | 58% | 1536.85 | 104 / 180 | 89% | 454.90 | 382 / 430 |
brain | 46% | 1481.97 | 1213 / 2642 | 96% | 639.50 | 675 / 705 |
esophagus | 68% | 2296.15 | 983 / 1445 | 72% | 202.59 | 132 / 183 |
kidney | 51% | 1839.56 | 45 / 89 | 85% | 431.11 | 768 / 901 |
prostate | 76% | 1920.32 | 185 / 245 | 58% | 91.97 | 293 / 502 |
uterus | 55% | 1298.89 | 94 / 170 | 77% | 284.62 | 354 / 459 |
pancreas | 41% | 745.29 | 136 / 328 | 87% | 327.48 | 154 / 178 |
thymus | 57% | 1459.47 | 373 / 653 | 64% | 162.90 | 388 / 605 |
skin | 24% | 401.86 | 431 / 1809 | 88% | 577.53 | 417 / 472 |
liver | 42% | 1658.45 | 94 / 226 | 67% | 191.64 | 272 / 406 |
lymph node | 0% | 0 | 0 / 0 | 100% | 1169.84 | 29 / 29 |
spleen | 99% | 41453.94 | 238 / 241 | 0% | 0 | 0 / 0 |
adipose | 97% | 8458.90 | 1169 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 377.64 | 41 / 45 |
blood vessel | 80% | 4396.29 | 1073 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 61% | 208.28 | 49 / 80 |
heart | 58% | 1627.39 | 501 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 32% | 1093.54 | 295 / 929 | 0% | 0 | 0 / 0 |
muscle | 10% | 144.58 | 78 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006955 | Biological process | immune response |
GO_0045650 | Biological process | negative regulation of macrophage differentiation |
GO_0006958 | Biological process | complement activation, classical pathway |
GO_0030853 | Biological process | negative regulation of granulocyte differentiation |
GO_0098883 | Biological process | synapse pruning |
GO_0045087 | Biological process | innate immune response |
GO_0005615 | Cellular component | extracellular space |
GO_0072562 | Cellular component | blood microparticle |
GO_0062167 | Cellular component | complement component C1q complex |
GO_0005581 | Cellular component | collagen trimer |
GO_0045202 | Cellular component | synapse |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0098794 | Cellular component | postsynapse |
GO_0005602 | Cellular component | complement component C1 complex |
GO_0005515 | Molecular function | protein binding |
Gene name | C1QC |
Protein name | Complement C1q subcomponent subunit C Complement C1q C chain Adiponectin B (Complement component 1, q subcomponent, C chain, isoform CRA_a) |
Synonyms | ADIB hCG_2037016 C1QG |
Description | FUNCTION: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Accessions | ENST00000695753.1 ENST00000374637.1 ENST00000695752.1 ENST00000374640.9 ENST00000695750.1 ENST00000695749.1 A0A8Q3WKR2 ENST00000695751.1 A0A024RAA7 P02747 ENST00000374639.7 A0A8Q3SIZ0 A0A8Q3WKR6 |