C1QC report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0045650Biological processnegative regulation of macrophage differentiation
GO_0006958Biological processcomplement activation, classical pathway
GO_0030853Biological processnegative regulation of granulocyte differentiation
GO_0098883Biological processsynapse pruning
GO_0045087Biological processinnate immune response
GO_0005615Cellular componentextracellular space
GO_0072562Cellular componentblood microparticle
GO_0062167Cellular componentcomplement component C1q complex
GO_0005581Cellular componentcollagen trimer
GO_0045202Cellular componentsynapse
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0098794Cellular componentpostsynapse
GO_0005602Cellular componentcomplement component C1 complex
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameC1QC
Protein nameComplement C1q subcomponent subunit C
Complement C1q C chain
Adiponectin B (Complement component 1, q subcomponent, C chain, isoform CRA_a)
SynonymsADIB
hCG_2037016
C1QG
DescriptionFUNCTION: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

AccessionsENST00000695753.1
ENST00000374637.1
ENST00000695752.1
ENST00000374640.9
ENST00000695750.1
ENST00000695749.1
A0A8Q3WKR2
ENST00000695751.1
A0A024RAA7
P02747
ENST00000374639.7
A0A8Q3SIZ0
A0A8Q3WKR6