NCF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045730Biological processrespiratory burst
GO_0006801Biological processsuperoxide metabolic process
GO_0006968Biological processcellular defense response
GO_0042554Biological processsuperoxide anion generation
GO_0006909Biological processphagocytosis
GO_0045087Biological processinnate immune response
GO_0001669Cellular componentacrosomal vesicle
GO_0005829Cellular componentcytosol
GO_0043020Cellular componentNADPH oxidase complex
GO_0016020Cellular componentmembrane
GO_0005886Cellular componentplasma membrane
GO_0032010Cellular componentphagolysosome
GO_0009055Molecular functionelectron transfer activity
GO_0016176Molecular functionsuperoxide-generating NADPH oxidase activator activity
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0016175Molecular functionsuperoxide-generating NAD(P)H oxidase activity

IV. Literature review

[source]
Gene nameNCF2
Protein nameNeutrophil cytosolic factor 2 isoform 1
Neutrophil cytosolic factor 2
Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox)
Neutrophil cytosol factor 2
Neutrophil cytosolic factor 2 isoform 3
SynonymsNOXA2
P67PHOX
DescriptionFUNCTION: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). .

AccessionsENST00000418089.5 [P19878-4]
ENST00000413720.5 [P19878-3]
ENST00000367535.8 [P19878-1]
A0A0S2Z457
A0A0S2Z4F9
Q0Q616
ENST00000697330.1 [P19878-1]
ENST00000697351.1
ENST00000367536.5 [P19878-1]
A0A8V8TMB9
P19878