Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 32 studies | 35% ± 14% | |
classical monocyte | 27 studies | 57% ± 16% | |
non-classical monocyte | 24 studies | 55% ± 15% | |
monocyte | 23 studies | 41% ± 14% | |
conventional dendritic cell | 19 studies | 39% ± 17% | |
myeloid cell | 14 studies | 36% ± 17% | |
dendritic cell | 13 studies | 34% ± 15% | |
neutrophil | 11 studies | 48% ± 16% | |
alveolar macrophage | 8 studies | 51% ± 17% | |
mononuclear phagocyte | 6 studies | 26% ± 13% | |
intermediate monocyte | 5 studies | 55% ± 23% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 12 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 6251.54 | 578 / 578 | 96% | 40.94 | 1108 / 1155 |
breast | 74% | 660.00 | 339 / 459 | 94% | 21.44 | 1055 / 1118 |
skin | 71% | 930.80 | 1279 / 1809 | 80% | 17.26 | 379 / 472 |
intestine | 64% | 470.28 | 616 / 966 | 75% | 15.95 | 396 / 527 |
esophagus | 54% | 402.92 | 786 / 1445 | 80% | 16.10 | 146 / 183 |
uterus | 34% | 197.44 | 57 / 170 | 88% | 22.77 | 406 / 459 |
kidney | 35% | 264.53 | 31 / 89 | 85% | 19.21 | 769 / 901 |
bladder | 48% | 545.52 | 10 / 21 | 72% | 18.17 | 364 / 504 |
thymus | 36% | 222.20 | 236 / 653 | 76% | 13.09 | 461 / 605 |
stomach | 32% | 247.33 | 115 / 359 | 79% | 14.95 | 227 / 286 |
pancreas | 19% | 162.22 | 63 / 328 | 90% | 34.25 | 161 / 178 |
lymph node | 0% | 0 | 0 / 0 | 100% | 98.44 | 29 / 29 |
peripheral blood | 100% | 50600.89 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 8503.91 | 241 / 241 | 0% | 0 | 0 / 0 |
brain | 14% | 97.80 | 374 / 2642 | 85% | 14.75 | 596 / 705 |
adipose | 98% | 1598.94 | 1179 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 34.51 | 44 / 45 |
liver | 34% | 237.81 | 77 / 226 | 60% | 13.08 | 242 / 406 |
adrenal gland | 65% | 451.06 | 168 / 258 | 21% | 2.24 | 48 / 230 |
prostate | 37% | 233.22 | 90 / 245 | 48% | 4.49 | 239 / 502 |
ovary | 18% | 106.85 | 33 / 180 | 65% | 7.91 | 278 / 430 |
blood vessel | 76% | 738.65 | 1008 / 1335 | 0% | 0 | 0 / 0 |
heart | 32% | 218.65 | 278 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 23% | 2.04 | 18 / 80 |
muscle | 3% | 15.49 | 27 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0045730 | Biological process | respiratory burst |
GO_0006801 | Biological process | superoxide metabolic process |
GO_0006968 | Biological process | cellular defense response |
GO_0042554 | Biological process | superoxide anion generation |
GO_0006909 | Biological process | phagocytosis |
GO_0045087 | Biological process | innate immune response |
GO_0001669 | Cellular component | acrosomal vesicle |
GO_0005829 | Cellular component | cytosol |
GO_0043020 | Cellular component | NADPH oxidase complex |
GO_0016020 | Cellular component | membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0032010 | Cellular component | phagolysosome |
GO_0009055 | Molecular function | electron transfer activity |
GO_0016176 | Molecular function | superoxide-generating NADPH oxidase activator activity |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0016175 | Molecular function | superoxide-generating NAD(P)H oxidase activity |
Gene name | NCF2 |
Protein name | Neutrophil cytosolic factor 2 isoform 1 Neutrophil cytosolic factor 2 Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox) Neutrophil cytosol factor 2 Neutrophil cytosolic factor 2 isoform 3 |
Synonyms | NOXA2 P67PHOX |
Description | FUNCTION: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). . |
Accessions | ENST00000418089.5 [P19878-4] ENST00000413720.5 [P19878-3] ENST00000367535.8 [P19878-1] A0A0S2Z457 A0A0S2Z4F9 Q0Q616 ENST00000697330.1 [P19878-1] ENST00000697351.1 ENST00000367536.5 [P19878-1] A0A8V8TMB9 P19878 |