Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 32 studies | 43% ± 18% | |
conventional dendritic cell | 30 studies | 46% ± 17% | |
classical monocyte | 24 studies | 37% ± 12% | |
plasmacytoid dendritic cell | 23 studies | 69% ± 17% | |
dendritic cell | 17 studies | 41% ± 19% | |
monocyte | 16 studies | 34% ± 16% | |
naive B cell | 13 studies | 25% ± 6% | |
B cell | 12 studies | 27% ± 10% | |
myeloid cell | 11 studies | 35% ± 13% | |
plasma cell | 7 studies | 35% ± 12% | |
memory B cell | 6 studies | 21% ± 5% | |
mononuclear phagocyte | 5 studies | 53% ± 20% | |
neutrophil | 5 studies | 33% ± 8% | |
leukocyte | 5 studies | 33% ± 11% | |
immature B cell | 5 studies | 20% ± 6% | |
intermediate monocyte | 4 studies | 38% ± 17% | |
monocyte-derived dendritic cell | 3 studies | 49% ± 19% | |
microglial cell | 3 studies | 38% ± 16% | |
non-classical monocyte | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 5 studies | 25% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 96% | 838.99 | 555 / 578 | 94% | 53.44 | 1085 / 1155 |
intestine | 95% | 711.61 | 922 / 966 | 94% | 36.71 | 496 / 527 |
breast | 89% | 445.38 | 410 / 459 | 98% | 55.95 | 1093 / 1118 |
prostate | 84% | 342.82 | 205 / 245 | 90% | 26.15 | 452 / 502 |
stomach | 72% | 241.30 | 257 / 359 | 92% | 45.93 | 264 / 286 |
adrenal gland | 93% | 594.84 | 240 / 258 | 67% | 19.79 | 153 / 230 |
bladder | 86% | 417.05 | 18 / 21 | 73% | 33.52 | 370 / 504 |
uterus | 65% | 205.52 | 111 / 170 | 83% | 30.45 | 382 / 459 |
esophagus | 67% | 243.46 | 972 / 1445 | 77% | 26.15 | 141 / 183 |
kidney | 53% | 291.16 | 47 / 89 | 91% | 62.72 | 818 / 901 |
skin | 52% | 154.02 | 933 / 1809 | 89% | 53.23 | 420 / 472 |
thymus | 57% | 212.09 | 372 / 653 | 83% | 36.78 | 504 / 605 |
ovary | 49% | 161.48 | 89 / 180 | 87% | 41.16 | 376 / 430 |
pancreas | 42% | 125.22 | 138 / 328 | 93% | 67.30 | 166 / 178 |
brain | 39% | 142.05 | 1036 / 2642 | 95% | 62.97 | 669 / 705 |
lymph node | 0% | 0 | 0 / 0 | 100% | 117.61 | 29 / 29 |
spleen | 100% | 2774.24 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 3161.47 | 926 / 929 | 0% | 0 | 0 / 0 |
liver | 30% | 87.15 | 68 / 226 | 67% | 21.16 | 274 / 406 |
adipose | 97% | 865.75 | 1162 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 45.08 | 40 / 45 |
blood vessel | 87% | 571.27 | 1156 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 53% | 16.38 | 42 / 80 |
heart | 47% | 145.88 | 404 / 861 | 0% | 0 | 0 / 0 |
muscle | 9% | 18.07 | 74 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050829 | Biological process | defense response to Gram-negative bacterium |
GO_0051607 | Biological process | defense response to virus |
GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
GO_0050830 | Biological process | defense response to Gram-positive bacterium |
GO_0019731 | Biological process | antibacterial humoral response |
GO_0045087 | Biological process | innate immune response |
GO_0006952 | Biological process | defense response |
GO_0006401 | Biological process | RNA catabolic process |
GO_0005615 | Cellular component | extracellular space |
GO_0005764 | Cellular component | lysosome |
GO_0005576 | Cellular component | extracellular region |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0004540 | Molecular function | RNA nuclease activity |
GO_0004519 | Molecular function | endonuclease activity |
GO_0003676 | Molecular function | nucleic acid binding |
Gene name | RNASE6 |
Protein name | Ribonuclease K6 (RNase K6) (EC 3.1.27.-) Ribonuclease K6 |
Synonyms | RAD1 hCG_1640892 RNS6 |
Description | FUNCTION: Ribonuclease which shows a preference for the pyrimidines uridine and cytosine . Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli . Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria . Probably contributes to urinary tract sterility . Bactericidal activity is independent of RNase activity . . |
Accessions | Q6IB39 ENST00000304677.3 Q93091 |