Insufficient scRNA-seq data for expression of TRIL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 4493.55 | 2617 / 2642 | 99% | 82.94 | 697 / 705 |
| breast | 85% | 1047.21 | 391 / 459 | 93% | 30.64 | 1038 / 1118 |
| thymus | 91% | 749.67 | 596 / 653 | 84% | 13.89 | 506 / 605 |
| kidney | 81% | 1011.69 | 72 / 89 | 69% | 11.07 | 618 / 901 |
| uterus | 86% | 818.21 | 147 / 170 | 39% | 16.74 | 180 / 459 |
| adrenal gland | 65% | 409.51 | 168 / 258 | 58% | 14.86 | 134 / 230 |
| ovary | 46% | 293.89 | 82 / 180 | 64% | 10.45 | 274 / 430 |
| esophagus | 58% | 466.52 | 834 / 1445 | 37% | 4.99 | 67 / 183 |
| skin | 44% | 314.04 | 801 / 1809 | 42% | 18.89 | 199 / 472 |
| lung | 42% | 257.75 | 244 / 578 | 39% | 5.70 | 452 / 1155 |
| spleen | 81% | 583.26 | 196 / 241 | 0% | 0 | 0 / 0 |
| prostate | 55% | 394.80 | 134 / 245 | 24% | 1.89 | 121 / 502 |
| stomach | 36% | 230.23 | 128 / 359 | 39% | 4.76 | 112 / 286 |
| intestine | 42% | 336.87 | 405 / 966 | 28% | 3.73 | 150 / 527 |
| adipose | 70% | 822.34 | 846 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 43% | 449.52 | 9 / 21 | 17% | 2.00 | 88 / 504 |
| pancreas | 2% | 7.45 | 5 / 328 | 46% | 3.66 | 82 / 178 |
| heart | 46% | 390.59 | 393 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 2.09 | 11 / 45 |
| blood vessel | 18% | 134.31 | 239 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 18% | 92.54 | 141 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.75 | 7 / 80 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.13 | 8 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034142 | Biological process | toll-like receptor 4 signaling pathway |
| GO_0006954 | Biological process | inflammatory response |
| GO_0002718 | Biological process | regulation of cytokine production involved in immune response |
| GO_0045087 | Biological process | innate immune response |
| GO_0046696 | Cellular component | lipopolysaccharide receptor complex |
| GO_0005615 | Cellular component | extracellular space |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0001530 | Molecular function | lipopolysaccharide binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TRIL |
| Protein name | TLR4 interactor with leucine rich repeats (Leucine-rich repeat-containing protein KIAA0644) |
| Synonyms | KIAA0644 |
| Description | FUNCTION: Component of the TLR4 signaling complex. Mediates the innate immune response to bacterial lipopolysaccharide (LPS) leading to cytokine secretion. . |
| Accessions | Q7L0X0 ENST00000539664.3 |