PGLYRP3 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of PGLYRP3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	38%	638.19	553 / 1445	63%	41.89	115 / 183
tonsil	0%	0	0 / 0	87%	38.18	39 / 45
skin	72%	1428.05	1296 / 1809	9%	2.42	42 / 472
uterus	1%	26.96	2 / 170	46%	20.65	213 / 459
lung	0%	0	0 / 578	36%	10.57	421 / 1155
bladder	0%	0	0 / 21	22%	5.65	111 / 504
pancreas	0%	0	0 / 328	7%	0.60	13 / 178
intestine	0%	0	0 / 966	6%	2.13	34 / 527
stomach	0%	0.55	1 / 359	4%	0.29	12 / 286
breast	0%	0	0 / 459	2%	0.41	24 / 1118
ovary	0%	0	0 / 180	1%	0.06	6 / 430
thymus	0%	0	0 / 653	1%	0.05	5 / 605
adipose	0%	1.07	2 / 1204	0%	0	0 / 0
muscle	0%	0.53	1 / 803	0%	0	0 / 0
kidney	0%	0	0 / 89	0%	0.02	1 / 901
blood vessel	0%	0.82	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	0%	0	0 / 230
bone marrow	0%	0	0 / 0	0%	0	0 / 0
brain	0%	0	0 / 2642	0%	0	0 / 705
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0	0 / 406
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0032689	Biological process	negative regulation of type II interferon production
GO_0009253	Biological process	peptidoglycan catabolic process
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0031640	Biological process	killing of cells of another organism
GO_0050830	Biological process	defense response to Gram-positive bacterium
GO_0051701	Biological process	biological process involved in interaction with host
GO_0016045	Biological process	detection of bacterium
GO_0045087	Biological process	innate immune response
GO_0032827	Biological process	negative regulation of natural killer cell differentiation involved in immune response
GO_0032991	Cellular component	protein-containing complex
GO_0005576	Cellular component	extracellular region
GO_0016020	Cellular component	membrane
GO_0046982	Molecular function	protein heterodimerization activity
GO_0008745	Molecular function	N-acetylmuramoyl-L-alanine amidase activity
GO_0042834	Molecular function	peptidoglycan binding
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding
GO_0016019	Molecular function	peptidoglycan immune receptor activity

Gene name	PGLYRP3
Protein name	Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha)
Synonyms	PGRPIA
Description	FUNCTION: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. .
Accessions	ENST00000290722.1 Q96LB9 ENST00000683862.1

PGLYRP3 report