Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| B cell | 11 studies | 22% ± 3% | |
| naive B cell | 8 studies | 22% ± 7% | |
| memory B cell | 6 studies | 20% ± 5% | |
| immature B cell | 3 studies | 27% ± 13% | |
| germinal center B cell | 3 studies | 21% ± 2% |
Insufficient scRNA-seq data for expression of CD180 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 93% | 259.87 | 537 / 578 | 89% | 4.89 | 1028 / 1155 |
| breast | 82% | 137.05 | 377 / 459 | 96% | 5.54 | 1072 / 1118 |
| intestine | 87% | 360.84 | 839 / 966 | 64% | 2.35 | 336 / 527 |
| stomach | 72% | 86.28 | 258 / 359 | 72% | 3.69 | 205 / 286 |
| bladder | 81% | 140.00 | 17 / 21 | 59% | 2.12 | 297 / 504 |
| kidney | 44% | 68.76 | 39 / 89 | 82% | 3.87 | 740 / 901 |
| brain | 46% | 49.77 | 1218 / 2642 | 79% | 3.52 | 557 / 705 |
| esophagus | 56% | 53.04 | 806 / 1445 | 68% | 2.02 | 125 / 183 |
| prostate | 71% | 74.09 | 173 / 245 | 48% | 1.09 | 239 / 502 |
| ovary | 34% | 25.39 | 61 / 180 | 77% | 2.70 | 333 / 430 |
| pancreas | 31% | 25.55 | 101 / 328 | 79% | 4.11 | 140 / 178 |
| uterus | 43% | 33.30 | 73 / 170 | 63% | 1.78 | 290 / 459 |
| adrenal gland | 82% | 112.83 | 212 / 258 | 22% | 0.47 | 51 / 230 |
| thymus | 48% | 89.91 | 315 / 653 | 55% | 2.11 | 333 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 66.28 | 29 / 29 |
| spleen | 100% | 2886.94 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 1138.80 | 919 / 929 | 0% | 0 | 0 / 0 |
| adipose | 90% | 190.24 | 1083 / 1204 | 0% | 0 | 0 / 0 |
| skin | 12% | 7.29 | 223 / 1809 | 76% | 4.60 | 359 / 472 |
| liver | 46% | 51.95 | 105 / 226 | 37% | 1.04 | 149 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 78% | 4.38 | 35 / 45 |
| blood vessel | 60% | 109.01 | 803 / 1335 | 0% | 0 | 0 / 0 |
| heart | 42% | 35.04 | 362 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 19% | 0.45 | 15 / 80 |
| muscle | 4% | 2.18 | 31 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0031663 | Biological process | lipopolysaccharide-mediated signaling pathway |
| GO_0006954 | Biological process | inflammatory response |
| GO_0002322 | Biological process | B cell proliferation involved in immune response |
| GO_0045087 | Biological process | innate immune response |
| GO_0031666 | Biological process | positive regulation of lipopolysaccharide-mediated signaling pathway |
| GO_0072686 | Cellular component | mitotic spindle |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CD180 |
| Protein name | CD180 antigen (Lymphocyte antigen 64) (Radioprotective 105 kDa protein) (CD antigen CD180) |
| Synonyms | RP105 LY64 |
| Description | FUNCTION: May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). . |
| Accessions | ENST00000256447.5 Q99467 |
