DDX60 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	5 studies	23% ± 5%	Explore
epithelial cell	4 studies	20% ± 4%	Explore
oligodendrocyte precursor cell	3 studies	25% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DDX60 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	97%	837.94	1399 / 1445	98%	39.03	180 / 183
breast	100%	1463.26	459 / 459	94%	35.21	1056 / 1118
thymus	100%	1378.40	653 / 653	94%	21.22	567 / 605
stomach	100%	1444.70	359 / 359	90%	20.18	257 / 286
lung	100%	1737.49	578 / 578	89%	21.08	1030 / 1155
prostate	100%	942.17	244 / 245	89%	16.55	447 / 502
intestine	100%	1871.47	966 / 966	87%	19.70	461 / 527
kidney	100%	1217.81	89 / 89	87%	18.67	780 / 901
uterus	100%	1454.45	170 / 170	86%	25.89	393 / 459
pancreas	86%	370.92	283 / 328	95%	27.66	169 / 178
bladder	100%	985.00	21 / 21	80%	19.16	403 / 504
ovary	100%	2001.24	180 / 180	79%	12.01	338 / 430
skin	100%	1079.59	1804 / 1809	77%	17.13	362 / 472
adrenal gland	99%	1145.70	255 / 258	69%	10.31	159 / 230
brain	73%	333.32	1935 / 2642	80%	9.88	561 / 705
liver	89%	462.85	201 / 226	63%	8.38	254 / 406
spleen	100%	1995.94	241 / 241	0%	0	0 / 0
adipose	100%	1618.31	1203 / 1204	0%	0	0 / 0
blood vessel	100%	1143.72	1331 / 1335	0%	0	0 / 0
heart	98%	638.03	842 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	32.37	42 / 45
peripheral blood	73%	1243.53	677 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	10.07	18 / 29
muscle	54%	194.39	434 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	31%	3.97	25 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0009615	Biological process	response to virus
GO_0051607	Biological process	defense response to virus
GO_1900246	Biological process	positive regulation of RIG-I signaling pathway
GO_1900245	Biological process	positive regulation of MDA-5 signaling pathway
GO_0045087	Biological process	innate immune response
GO_0045111	Cellular component	intermediate filament cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0003725	Molecular function	double-stranded RNA binding
GO_0003690	Molecular function	double-stranded DNA binding
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding
GO_0003727	Molecular function	single-stranded RNA binding
GO_0003724	Molecular function	RNA helicase activity
GO_0016887	Molecular function	ATP hydrolysis activity

Gene name	DDX60
Protein name	ATP-dependent RNA helicase DDX60 DExD/H-box helicase 60 DDX60 protein (cDNA: FLJ22680 fis, clone HSI10688) DDX60 protein Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60)
Synonyms	hCG_1811383 FLJ20035
Description	FUNCTION: Positively regulates RIGI- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of RIGI to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). .
Accessions	A0A7P0T9W8 A0A7P0T8Y0 ENST00000680771.1 ENST00000393743.8 A0A3G9HN97 Q6B0F7 H0Y9B2 ENST00000513997.1 Q8IY21 H0Y8Z7 ENST00000680917.1 D6R944 Q9H616 ENST00000514995.2 ENST00000511317.2 A0A7P0TAZ7 ENST00000679510.1

DDX60 report