CLEC5A | OmnibusX

Name	Number of supported studies	Average coverage
myeloid cell	3 studies	19% ± 2%	Explore
conventional dendritic cell	3 studies	21% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLEC5A at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	99%	582.08	575 / 578	88%	6.00	1014 / 1155
pancreas	76%	117.63	250 / 328	88%	4.92	156 / 178
thymus	85%	112.72	552 / 653	76%	2.97	462 / 605
ovary	43%	41.82	77 / 180	85%	4.50	367 / 430
kidney	51%	58.31	45 / 89	76%	3.13	688 / 901
breast	39%	30.45	179 / 459	85%	5.32	952 / 1118
adrenal gland	95%	229.86	245 / 258	20%	0.45	46 / 230
skin	65%	81.53	1181 / 1809	49%	1.65	231 / 472
uterus	45%	36.02	76 / 170	69%	2.25	316 / 459
esophagus	43%	43.17	616 / 1445	64%	2.30	118 / 183
blood vessel	96%	262.38	1284 / 1335	0%	0	0 / 0
bladder	38%	152.33	8 / 21	53%	2.51	269 / 504
stomach	25%	18.64	88 / 359	61%	2.25	174 / 286
brain	40%	73.98	1053 / 2642	45%	4.55	319 / 705
spleen	84%	153.43	202 / 241	0%	0	0 / 0
peripheral blood	82%	571.88	761 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	78%	2.73	35 / 45
prostate	60%	62.77	148 / 245	9%	0.14	43 / 502
intestine	16%	14.51	152 / 966	51%	2.18	269 / 527
heart	43%	41.07	367 / 861	0%	0	0 / 0
adipose	42%	35.63	500 / 1204	0%	0	0 / 0
liver	14%	13.21	31 / 226	17%	0.48	68 / 406
lymph node	0%	0	0 / 0	17%	0.68	5 / 29
muscle	1%	0.45	6 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0046718	Biological process	symbiont entry into host cell
GO_0001819	Biological process	positive regulation of cytokine production
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0030099	Biological process	myeloid cell differentiation
GO_0002076	Biological process	osteoblast development
GO_0006968	Biological process	cellular defense response
GO_0033033	Biological process	negative regulation of myeloid cell apoptotic process
GO_0045087	Biological process	innate immune response
GO_0009986	Cellular component	cell surface
GO_0005829	Cellular component	cytosol
GO_0035579	Cellular component	specific granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0070821	Cellular component	tertiary granule membrane
GO_0030246	Molecular function	carbohydrate binding
GO_0001618	Molecular function	virus receptor activity

Gene name	CLEC5A
Protein name	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin 1) (MDL-1) C-type (Calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 (C-type lectin domain family 5, member A, isoform CRA_b) (cDNA FLJ78045, highly similar to Homo sapiens C-type lectin domain family 5, member A (CLEC5A), mRNA) C-type lectin domain containing 5A (CLEC5A protein) (cDNA FLJ51846, highly similar to C-type lectin domain family 5 member A) C-type lectin domain containing 5A
Synonyms	MDL1 CLECSF5 tcag7.335 hCG_39448
Description	FUNCTION: Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP . Regulates inflammatory responses (By similarity). .; FUNCTION: (Microbial infection) Critical macrophage receptor for dengue virus serotypes 1-4 . The binding of dengue virus to CLEC5A triggers signaling through the phosphorylation of TYROBP . This interaction does not result in viral entry, but stimulates pro-inflammatory cytokine release . .
Accessions	A4D1U7 ENST00000551012.6 Q9NY25 ENST00000546910.6 [Q9NY25-1] C9JPR7 Q14DL9 C9JCE4 ENST00000418498.5 F8WCL0 ENST00000438351.1 ENST00000439991.1

CLEC5A report