C4BPB | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	5 studies	66% ± 14%	Explore

Name	Number of supported studies	Average coverage
liver	3 studies	34% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	15230.46	226 / 226	97%	223.52	394 / 406
pancreas	96%	321.63	314 / 328	80%	14.04	142 / 178
stomach	89%	343.72	320 / 359	77%	8.59	221 / 286
intestine	67%	158.20	652 / 966	87%	10.65	459 / 527
lung	98%	140.14	564 / 578	42%	6.60	480 / 1155
ovary	97%	1643.72	174 / 180	2%	0.12	9 / 430
bladder	67%	22.90	14 / 21	31%	3.39	155 / 504
breast	70%	76.40	322 / 459	12%	0.97	132 / 1118
adipose	74%	65.33	891 / 1204	0%	0	0 / 0
esophagus	23%	11.03	327 / 1445	45%	11.33	83 / 183
kidney	61%	19.08	54 / 89	7%	0.52	62 / 901
spleen	59%	30.35	141 / 241	0%	0	0 / 0
blood vessel	33%	17.60	439 / 1335	0%	0	0 / 0
peripheral blood	32%	41.69	299 / 929	0%	0	0 / 0
adrenal gland	26%	7.51	66 / 258	4%	0.21	10 / 230
uterus	11%	7.15	19 / 170	15%	6.48	70 / 459
skin	23%	7.57	412 / 1809	0%	0.01	2 / 472
muscle	10%	2.81	84 / 803	0%	0	0 / 0
prostate	7%	2.25	17 / 245	0%	0	0 / 502
lymph node	0%	0	0 / 0	7%	0.19	2 / 29
heart	7%	2.15	56 / 861	0%	0	0 / 0
thymus	4%	1.05	23 / 653	1%	0.04	6 / 605
brain	1%	0.38	14 / 2642	0%	0.01	2 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0045732	Biological process	positive regulation of protein catabolic process
GO_0006958	Biological process	complement activation, classical pathway
GO_1903027	Biological process	regulation of opsonization
GO_0007596	Biological process	blood coagulation
GO_0045959	Biological process	negative regulation of complement activation, classical pathway
GO_0045087	Biological process	innate immune response
GO_0009609	Biological process	response to symbiotic bacterium
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0005515	Molecular function	protein binding

Gene name	C4BPB
Protein name	C4b-binding protein beta chain Complement component 4 binding protein beta
Synonyms
Description	FUNCTION: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Accessions	ENST00000391923.1 [P20851-1] ENST00000367078.8 [P20851-1] P20851 ENST00000243611.9 [P20851-1] ENST00000452902.6 Q5VVQ7 ENST00000367076.7 [P20851-2]

C4BPB report