Name | Number of supported studies | Average coverage | |
---|---|---|---|
conventional dendritic cell | 28 studies | 46% ± 14% | |
dendritic cell | 16 studies | 42% ± 19% | |
macrophage | 15 studies | 29% ± 16% | |
monocyte | 11 studies | 28% ± 9% | |
mononuclear phagocyte | 5 studies | 44% ± 22% | |
monocyte-derived dendritic cell | 4 studies | 47% ± 29% | |
classical monocyte | 4 studies | 20% ± 4% | |
myeloid cell | 4 studies | 28% ± 7% | |
leukocyte | 3 studies | 19% ± 3% |
Insufficient scRNA-seq data for expression of CLEC10A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 95% | 537.16 | 549 / 578 | 80% | 8.73 | 920 / 1155 |
prostate | 81% | 251.38 | 199 / 245 | 77% | 5.13 | 385 / 502 |
liver | 87% | 228.83 | 197 / 226 | 68% | 4.78 | 278 / 406 |
breast | 95% | 404.24 | 434 / 459 | 61% | 6.33 | 678 / 1118 |
bladder | 100% | 518.62 | 21 / 21 | 53% | 4.61 | 269 / 504 |
thymus | 83% | 224.84 | 539 / 653 | 71% | 6.25 | 427 / 605 |
intestine | 100% | 667.85 | 962 / 966 | 50% | 3.38 | 266 / 527 |
uterus | 85% | 224.36 | 144 / 170 | 57% | 4.60 | 261 / 459 |
skin | 64% | 207.81 | 1158 / 1809 | 66% | 8.48 | 313 / 472 |
kidney | 55% | 174.35 | 49 / 89 | 73% | 6.81 | 662 / 901 |
esophagus | 93% | 368.58 | 1351 / 1445 | 35% | 1.83 | 64 / 183 |
stomach | 73% | 210.28 | 261 / 359 | 56% | 3.79 | 159 / 286 |
adrenal gland | 80% | 220.69 | 206 / 258 | 27% | 1.51 | 63 / 230 |
lymph node | 0% | 0 | 0 / 0 | 100% | 37.81 | 29 / 29 |
adipose | 98% | 864.33 | 1181 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 21% | 33.46 | 70 / 328 | 73% | 8.60 | 130 / 178 |
spleen | 94% | 573.17 | 227 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 85% | 311.64 | 1135 / 1335 | 0% | 0 | 0 / 0 |
heart | 78% | 201.52 | 673 / 861 | 0% | 0 | 0 / 0 |
ovary | 44% | 96.72 | 80 / 180 | 33% | 1.83 | 140 / 430 |
peripheral blood | 75% | 468.64 | 696 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 71% | 9.20 | 32 / 45 |
muscle | 44% | 64.74 | 351 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 26% | 1.03 | 21 / 80 |
brain | 0% | 0.65 | 13 / 2642 | 16% | 1.06 | 110 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002250 | Biological process | adaptive immune response |
GO_0006897 | Biological process | endocytosis |
GO_0044419 | Biological process | biological process involved in interspecies interaction between organisms |
GO_0045087 | Biological process | innate immune response |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0042806 | Molecular function | fucose binding |
GO_0005537 | Molecular function | D-mannose binding |
GO_0030246 | Molecular function | carbohydrate binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CLEC10A |
Protein name | C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301) C-type lectin domain family 10, member A, isoform CRA_c (cDNA FLJ78539, highly similar to Homo sapiens C-type lectin domain family 10, member A, mRNA) C-type lectin domain containing 10A |
Synonyms | CLECSF13 CLECSF14 HML hCG_1777068 |
Description | FUNCTION: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. . |
Accessions | ENST00000416562.7 ENST00000254868.8 [Q8IUN9-1] ENST00000571664.1 [Q8IUN9-2] I3NI09 ENST00000576617.5 [Q8IUN9-3] ENST00000576549.6 Q8IUN9 A8K7G0 J3KR22 |