CLEC10A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLEC10A at tissue level.

III. Associated gene sets

GO_0002250Biological processadaptive immune response
GO_0006897Biological processendocytosis
GO_0044419Biological processbiological process involved in interspecies interaction between organisms
GO_0045087Biological processinnate immune response
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0042806Molecular functionfucose binding
GO_0005537Molecular functionD-mannose binding
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCLEC10A
Protein nameC-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301)
C-type lectin domain family 10, member A, isoform CRA_c (cDNA FLJ78539, highly similar to Homo sapiens C-type lectin domain family 10, member A, mRNA)
C-type lectin domain containing 10A
SynonymsCLECSF13
CLECSF14
HML
hCG_1777068
DescriptionFUNCTION: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. .

AccessionsENST00000416562.7
ENST00000254868.8 [Q8IUN9-1]
ENST00000571664.1 [Q8IUN9-2]
I3NI09
ENST00000576617.5 [Q8IUN9-3]
ENST00000576549.6
Q8IUN9
A8K7G0
J3KR22