Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 12 studies | 23% ± 7% | |
adipocyte | 9 studies | 35% ± 6% | |
retinal ganglion cell | 6 studies | 53% ± 22% | |
epithelial cell | 6 studies | 29% ± 10% | |
type I pneumocyte | 6 studies | 24% ± 7% | |
type II pneumocyte | 6 studies | 22% ± 5% | |
macrophage | 6 studies | 27% ± 7% | |
myeloid cell | 5 studies | 19% ± 5% | |
ciliated cell | 5 studies | 21% ± 3% | |
squamous epithelial cell | 4 studies | 37% ± 17% | |
neuron | 4 studies | 32% ± 16% | |
cardiac muscle cell | 4 studies | 20% ± 2% | |
basal cell | 4 studies | 26% ± 13% | |
monocyte | 4 studies | 21% ± 4% | |
club cell | 4 studies | 21% ± 7% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 4% | |
fibroblast | 4 studies | 19% ± 3% | |
astrocyte | 4 studies | 32% ± 10% | |
interneuron | 4 studies | 34% ± 21% | |
oligodendrocyte | 4 studies | 22% ± 4% | |
hepatocyte | 3 studies | 46% ± 19% | |
alveolar macrophage | 3 studies | 26% ± 8% | |
glutamatergic neuron | 3 studies | 44% ± 22% | |
GABAergic neuron | 3 studies | 39% ± 19% | |
microglial cell | 3 studies | 26% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 7626.72 | 459 / 459 | 100% | 120.80 | 1118 / 1118 |
esophagus | 100% | 8872.37 | 1445 / 1445 | 100% | 103.87 | 183 / 183 |
liver | 100% | 8356.92 | 226 / 226 | 100% | 139.65 | 406 / 406 |
stomach | 100% | 5859.58 | 359 / 359 | 100% | 80.60 | 286 / 286 |
thymus | 100% | 7360.41 | 653 / 653 | 100% | 117.73 | 605 / 605 |
lung | 100% | 9118.49 | 578 / 578 | 100% | 114.74 | 1153 / 1155 |
uterus | 100% | 6101.92 | 170 / 170 | 100% | 128.59 | 458 / 459 |
skin | 100% | 6698.68 | 1808 / 1809 | 100% | 154.79 | 471 / 472 |
intestine | 100% | 7672.61 | 966 / 966 | 100% | 87.46 | 525 / 527 |
bladder | 100% | 8397.33 | 21 / 21 | 100% | 105.31 | 502 / 504 |
prostate | 100% | 6814.62 | 244 / 245 | 100% | 97.87 | 502 / 502 |
kidney | 100% | 7141.18 | 89 / 89 | 99% | 109.89 | 894 / 901 |
brain | 99% | 8371.20 | 2625 / 2642 | 100% | 70.21 | 702 / 705 |
pancreas | 99% | 3377.25 | 324 / 328 | 100% | 105.74 | 178 / 178 |
ovary | 100% | 4926.61 | 180 / 180 | 99% | 67.64 | 424 / 430 |
adrenal gland | 100% | 7110.72 | 258 / 258 | 97% | 71.88 | 223 / 230 |
adipose | 100% | 8020.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 184.92 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 129.48 | 29 / 29 |
muscle | 100% | 24433.34 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 6473.16 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 131.94 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 156.85 | 1 / 1 |
blood vessel | 100% | 8096.46 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 9276.30 | 849 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 6725.83 | 900 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045087 | Biological process | innate immune response |
GO_0032480 | Biological process | negative regulation of type I interferon production |
GO_1900181 | Biological process | negative regulation of protein localization to nucleus |
GO_0016236 | Biological process | macroautophagy |
GO_0032720 | Biological process | negative regulation of tumor necrosis factor production |
GO_0050687 | Biological process | negative regulation of defense response to virus |
GO_0043392 | Biological process | negative regulation of DNA binding |
GO_0016607 | Cellular component | nuclear speck |
GO_0005813 | Cellular component | centrosome |
GO_0005829 | Cellular component | cytosol |
GO_0000407 | Cellular component | phagophore assembly site |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0043130 | Molecular function | ubiquitin binding |
Gene name | ILRUN |
Protein name | Protein ILRUN (Inflammation and lipid regulator with UBA-like and NBR1-like domains protein) Alternative protein C6orf106 Inflammation and lipid regulator with UBA-like and NBR1-like domains |
Synonyms | C6orf106 |
Description | FUNCTION: Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF . Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP . . |
Accessions | Q5TH58 ENST00000374023.8 [Q9H6K1-1] L8EB61 ENST00000374026.7 [Q9H6K1-2] ENST00000374021.1 Q9H6K1 |