GO_0032480 | negative regulation of type I interferon production | OmnibusX

negative regulation of type I interferon production

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	SIGLEC1 RBX1 TYROBP	macrophage	5 studies
Group 2	KLHL22 UFD1 ITCH NPLOC4 CYLD KAT8 PTPN11 RNF216 ILRUN ATG5 ATG12 CUL3 TRAF3IP1	dopaminergic neuron	5 studies
Group 3	RNF125 XAF1 BANF1	CD16-negative, CD56-bright natural killer cell, human CD16-positive, CD56-dim natural killer cell, human natural killer cell	11 studies
Group 4	OTUD5 DDX56 TRIM27	epithelial cell plasma cell	6 studies

II. Literature review

Name	negative regulation of type I interferon production
ID	GO_0032480
collection_id	Biological process
Exact synonym	down regulation of type I interferon production, down-regulation of type I interferon production, downregulation of type I interferon production, negative regulation of type I IFN production
Description	Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
External URL
Genes	XAF1 TYROBP ATG5 IRGM NPLOC4 ITCH RNF125 BANF1 GBP7 GPATCH3 ILRUN OTUD5 DDX56 ATG12 CUL3 SIGLEC1 KLHL22 TRIM27 DHX58 TRAF3IP1 PTPN11 UFD1 RNF216 CYLD URS000039ED8D_9606 atg5-atg12_human KAT8 ACOD1 RBX1