PTX3 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell of lymphatic vessel	10 studies	29% ± 17%	Explore
fibroblast	7 studies	21% ± 4%	Explore
classical monocyte	3 studies	19% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PTX3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	78%	6977.75	450 / 578	48%	4.42	549 / 1155
breast	69%	4666.63	318 / 459	42%	9.15	472 / 1118
skin	49%	39098.15	889 / 1809	53%	7.89	248 / 472
pancreas	37%	517.66	120 / 328	63%	11.51	112 / 178
ovary	2%	14.91	4 / 180	90%	23.01	387 / 430
bladder	52%	1906.76	11 / 21	36%	5.52	182 / 504
adipose	80%	14574.88	966 / 1204	0%	0	0 / 0
spleen	74%	839.59	178 / 241	0%	0	0 / 0
brain	0%	6.66	13 / 2642	66%	23.48	463 / 705
adrenal gland	33%	779.18	86 / 258	27%	7.25	63 / 230
stomach	39%	1967.36	140 / 359	19%	1.02	53 / 286
thymus	20%	342.39	131 / 653	32%	1.74	196 / 605
esophagus	21%	622.24	300 / 1445	31%	3.90	56 / 183
blood vessel	49%	2086.70	659 / 1335	0%	0	0 / 0
uterus	8%	143.12	14 / 170	37%	12.17	172 / 459
intestine	29%	767.42	278 / 966	16%	1.98	84 / 527
kidney	13%	492.78	12 / 89	27%	2.47	241 / 901
heart	33%	2000.50	288 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	24%	4.30	11 / 45
prostate	13%	440.62	31 / 245	8%	0.54	41 / 502
peripheral blood	19%	262.87	179 / 929	0%	0	0 / 0
liver	3%	93.06	6 / 226	14%	1.17	58 / 406
muscle	8%	209.44	62 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	7%	0.38	2 / 29
eye	0%	0	0 / 0	3%	0.11	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0044871	Biological process	negative regulation by host of viral glycoprotein metabolic process
GO_0044793	Biological process	negative regulation by host of viral process
GO_0050766	Biological process	positive regulation of phagocytosis
GO_0006954	Biological process	inflammatory response
GO_0045087	Biological process	innate immune response
GO_0030198	Biological process	extracellular matrix organization
GO_0044869	Biological process	negative regulation by host of viral exo-alpha-sialidase activity
GO_0046597	Biological process	negative regulation of viral entry into host cell
GO_1903019	Biological process	negative regulation of glycoprotein metabolic process
GO_1903016	Biological process	negative regulation of exo-alpha-sialidase activity
GO_0045429	Biological process	positive regulation of nitric oxide biosynthetic process
GO_0001550	Biological process	ovarian cumulus expansion
GO_0001878	Biological process	response to yeast
GO_0008228	Biological process	opsonization
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0035580	Cellular component	specific granule lumen
GO_0031012	Cellular component	extracellular matrix
GO_1904724	Cellular component	tertiary granule lumen
GO_0001872	Molecular function	(1->3)-beta-D-glucan binding
GO_0042802	Molecular function	identical protein binding
GO_0001849	Molecular function	complement component C1q complex binding
GO_0005515	Molecular function	protein binding
GO_0046790	Molecular function	virion binding

Gene name	PTX3
Protein name	Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)
Synonyms	TNFAIP5 TSG14
Description	FUNCTION: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. .
Accessions	P26022 ENST00000295927.4

PTX3 report