NLRC5 | OmnibusX

Name	Number of supported studies	Average coverage
T cell	12 studies	23% ± 9%	Explore
CD8-positive, alpha-beta T cell	11 studies	25% ± 7%	Explore
B cell	8 studies	20% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	19% ± 2%	Explore
regulatory T cell	7 studies	18% ± 3%	Explore
endothelial cell	7 studies	22% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	26% ± 7%	Explore
natural killer cell	6 studies	24% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	21% ± 3%	Explore
CD4-positive, alpha-beta T cell	5 studies	22% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	22% ± 5%	Explore
mature NK T cell	4 studies	21% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	21% ± 4%	Explore
classical monocyte	3 studies	25% ± 7%	Explore
exhausted T cell	3 studies	27% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	25% ± 5%	Explore
non-classical monocyte	3 studies	22% ± 6%	Explore
dendritic cell	3 studies	24% ± 5%	Explore
endothelial cell of lymphatic vessel	3 studies	20% ± 6%	Explore
monocyte	3 studies	20% ± 2%	Explore
lymphocyte	3 studies	42% ± 9%	Explore
microglial cell	3 studies	26% ± 4%	Explore
gamma-delta T cell	3 studies	16% ± 1%	Explore

Name	Number of supported studies	Average coverage
peripheral blood	4 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	4148.92	963 / 966	99%	21.00	520 / 527
lung	100%	5748.28	578 / 578	97%	15.35	1120 / 1155
esophagus	97%	1764.79	1397 / 1445	99%	27.37	182 / 183
uterus	100%	3081.20	170 / 170	94%	18.72	431 / 459
breast	100%	2823.21	459 / 459	93%	12.21	1042 / 1118
skin	100%	4101.63	1807 / 1809	92%	15.62	436 / 472
stomach	94%	1673.33	336 / 359	98%	19.96	281 / 286
kidney	97%	2040.90	86 / 89	93%	12.36	841 / 901
thymus	100%	2654.36	650 / 653	86%	8.08	523 / 605
bladder	100%	2174.19	21 / 21	85%	14.03	427 / 504
adrenal gland	100%	2290.56	258 / 258	81%	6.02	187 / 230
prostate	98%	2311.57	241 / 245	68%	4.72	341 / 502
ovary	90%	1287.09	162 / 180	69%	5.42	295 / 430
liver	85%	1271.17	193 / 226	63%	5.32	257 / 406
pancreas	43%	479.46	142 / 328	96%	12.74	170 / 178
brain	28%	325.85	731 / 2642	80%	6.97	565 / 705
adipose	100%	3508.04	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	44.73	29 / 29
spleen	100%	16812.82	241 / 241	0%	0	0 / 0
peripheral blood	100%	11864.31	928 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	22.03	44 / 45
blood vessel	84%	1452.76	1120 / 1335	0%	0	0 / 0
heart	80%	959.48	687 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	43%	5.26	34 / 80
muscle	27%	254.36	215 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0045087	Biological process	innate immune response
GO_0060335	Biological process	positive regulation of type II interferon-mediated signaling pathway
GO_0051607	Biological process	defense response to virus
GO_0043549	Biological process	regulation of kinase activity
GO_0060339	Biological process	negative regulation of type I interferon-mediated signaling pathway
GO_0035556	Biological process	intracellular signal transduction
GO_0045345	Biological process	positive regulation of MHC class I biosynthetic process
GO_0060340	Biological process	positive regulation of type I interferon-mediated signaling pathway
GO_0032088	Biological process	negative regulation of NF-kappaB transcription factor activity
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0009617	Biological process	response to bacterium
GO_0005813	Cellular component	centrosome
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding

Gene name	NLRC5
Protein name	NLR family CARD domain containing 5 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4)
Synonyms	NOD4 NOD27
Description	FUNCTION: Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. .
Accessions	ENST00000545349.1 ENST00000538453.5 H0YGE2 ENST00000538805.5 ENST00000537056.5 H0YGV6 H0YF88 H0YGT6 Q86WI3 ENST00000262510.10 [Q86WI3-1] H0YG32 F5GYP0 H0YFT1 ENST00000545081.5 ENST00000688547.1 [Q86WI3-1] F5H274 ENST00000544641.5 ENST00000399221.3 ENST00000538110.5 H0YFT3 ENST00000538059.5 ENST00000539881.5 [Q86WI3-3] H0YFG4 ENST00000540182.5 ENST00000543030.5 H0YGM1 ENST00000539144.5 [Q86WI3-4]

NLRC5 report