Insufficient scRNA-seq data for expression of SSC5D at single-cell level.
Insufficient scRNA-seq data for expression of SSC5D at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 95% | 1862.38 | 437 / 459 | 93% | 14.80 | 1036 / 1118 |
prostate | 93% | 1963.27 | 229 / 245 | 88% | 7.40 | 443 / 502 |
lung | 96% | 1809.03 | 552 / 578 | 85% | 10.27 | 987 / 1155 |
ovary | 100% | 2892.15 | 180 / 180 | 73% | 7.45 | 315 / 430 |
uterus | 99% | 6689.33 | 169 / 170 | 63% | 8.29 | 289 / 459 |
intestine | 92% | 4375.64 | 889 / 966 | 67% | 6.71 | 355 / 527 |
bladder | 100% | 2203.10 | 21 / 21 | 59% | 5.77 | 295 / 504 |
skin | 83% | 1595.70 | 1496 / 1809 | 72% | 6.41 | 338 / 472 |
esophagus | 81% | 2929.83 | 1173 / 1445 | 72% | 6.86 | 132 / 183 |
thymus | 78% | 794.74 | 509 / 653 | 65% | 3.85 | 392 / 605 |
stomach | 58% | 1700.91 | 210 / 359 | 74% | 10.66 | 211 / 286 |
kidney | 58% | 546.63 | 52 / 89 | 67% | 7.27 | 603 / 901 |
adrenal gland | 38% | 268.00 | 98 / 258 | 76% | 31.75 | 174 / 230 |
pancreas | 8% | 56.07 | 26 / 328 | 92% | 16.96 | 164 / 178 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.91 | 1 / 1 |
spleen | 100% | 2505.76 | 240 / 241 | 0% | 0 | 0 / 0 |
adipose | 98% | 2459.63 | 1185 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 94% | 2059.55 | 1249 / 1335 | 0% | 0 | 0 / 0 |
heart | 78% | 1611.84 | 672 / 861 | 0% | 0 | 0 / 0 |
brain | 32% | 284.86 | 849 / 2642 | 40% | 2.37 | 280 / 705 |
lymph node | 0% | 0 | 0 / 0 | 48% | 1.58 | 14 / 29 |
tonsil | 0% | 0 | 0 / 0 | 40% | 2.22 | 18 / 45 |
eye | 0% | 0 | 0 / 0 | 39% | 2.18 | 31 / 80 |
liver | 8% | 60.76 | 19 / 226 | 24% | 1.28 | 97 / 406 |
muscle | 23% | 194.96 | 186 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0050829 | Biological process | defense response to Gram-negative bacterium |
GO_0006952 | Biological process | defense response |
GO_0016192 | Biological process | vesicle-mediated transport |
GO_0050830 | Biological process | defense response to Gram-positive bacterium |
GO_0042494 | Biological process | detection of bacterial lipoprotein |
GO_0032717 | Biological process | negative regulation of interleukin-8 production |
GO_0045087 | Biological process | innate immune response |
GO_0005615 | Cellular component | extracellular space |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0016020 | Cellular component | membrane |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005737 | Cellular component | cytoplasm |
GO_0043236 | Molecular function | laminin binding |
GO_0050840 | Molecular function | extracellular matrix binding |
GO_0001968 | Molecular function | fibronectin binding |
GO_0005515 | Molecular function | protein binding |
GO_0005044 | Molecular function | scavenger receptor activity |
Gene name | SSC5D |
Protein name | Scavenger receptor cysteine rich family member with 5 domains Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Soluble scavenger protein with 5 SRCR domains) (SSc5D) |
Synonyms | |
Description | FUNCTION: Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity). . |
Accessions | ENST00000389623.11 [A1L4H1-1] ENST00000587166.5 [A1L4H1-2] K7EPL3 A1L4H1 M0QZ17 ENST00000594321.5 ENST00000589020.1 |