SEC14L1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015871Biological processcholine transport
GO_0039536Biological processnegative regulation of RIG-I signaling pathway
GO_0045087Biological processinnate immune response
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0039552Molecular functionRIG-I binding
GO_0140311Molecular functionprotein sequestering activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSEC14L1
Protein nameSEC14L1 protein
SEC14 like lipid binding 1
SEC14 like lipid binding 1 (SEC14L1 protein)
SEC14-like protein 1
SynonymsSEC14L
DescriptionFUNCTION: May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of RIGI, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of RIGI with MAVS/IPS1, an important step in signal propagation . May also regulate the SLC18A3 and SLC5A7 cholinergic transporters . .

AccessionsK7EIJ7
ENST00000591786.5
ENST00000430767.8 [Q92503-1]
K7ERB3
D5G3K4
K7EJ08
ENST00000589827.5
ENST00000431431.6 [Q92503-3]
K7EQK4
ENST00000588488.1
ENST00000585618.5 [Q92503-1]
ENST00000587820.1
ENST00000443798.8 [Q92503-2]
ENST00000590483.1
K7EJJ2
ENST00000588880.5
ENST00000591437.5 [Q92503-3]
ENST00000561721.6
ENST00000589202.1
ENST00000588616.6
K7EPE4
K7ESI4
A5PLM6
K7ELM0
Q92503
ENST00000436233.9 [Q92503-1]
ENST00000392476.6 [Q92503-2]
K7ELU0
ENST00000586429.5
D5G3K3