I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 36% ± 23% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 36% ± 23% |
Insufficient scRNA-seq data for expression of VNN1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 6625.43 | 226 / 226 | 87% | 93.40 | 352 / 406 |
| kidney | 91% | 1350.49 | 81 / 89 | 63% | 36.95 | 568 / 901 |
| lung | 99% | 723.00 | 570 / 578 | 40% | 10.79 | 466 / 1155 |
| pancreas | 47% | 125.77 | 154 / 328 | 84% | 44.98 | 149 / 178 |
| intestine | 51% | 544.23 | 493 / 966 | 56% | 18.68 | 294 / 527 |
| stomach | 41% | 119.05 | 146 / 359 | 58% | 28.05 | 167 / 286 |
| spleen | 98% | 1536.78 | 237 / 241 | 0% | 0 | 0 / 0 |
| adipose | 92% | 366.00 | 1104 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 30% | 62.13 | 432 / 1445 | 57% | 41.11 | 104 / 183 |
| breast | 74% | 171.80 | 341 / 459 | 12% | 1.54 | 138 / 1118 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 13.80 | 24 / 29 |
| peripheral blood | 81% | 10053.24 | 756 / 929 | 0% | 0 | 0 / 0 |
| uterus | 16% | 31.47 | 27 / 170 | 31% | 7.92 | 140 / 459 |
| blood vessel | 40% | 90.45 | 538 / 1335 | 0% | 0 | 0 / 0 |
| skin | 28% | 44.81 | 504 / 1809 | 11% | 0.71 | 50 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 38% | 11.85 | 17 / 45 |
| ovary | 10% | 11.88 | 18 / 180 | 27% | 2.96 | 118 / 430 |
| bladder | 14% | 16.90 | 3 / 21 | 19% | 4.35 | 95 / 504 |
| thymus | 29% | 43.79 | 188 / 653 | 3% | 0.17 | 18 / 605 |
| adrenal gland | 27% | 37.36 | 70 / 258 | 2% | 0.70 | 5 / 230 |
| prostate | 18% | 26.02 | 43 / 245 | 4% | 0.46 | 20 / 502 |
| heart | 20% | 34.45 | 176 / 861 | 0% | 0 | 0 / 0 |
| brain | 4% | 4.58 | 105 / 2642 | 5% | 0.29 | 34 / 705 |
| muscle | 7% | 7.37 | 54 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.05 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902177 | Biological process | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
| GO_0033089 | Biological process | positive regulation of T cell differentiation in thymus |
| GO_0002544 | Biological process | chronic inflammatory response |
| GO_0015939 | Biological process | pantothenate metabolic process |
| GO_0006954 | Biological process | inflammatory response |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0002526 | Biological process | acute inflammatory response |
| GO_0006979 | Biological process | response to oxidative stress |
| GO_0015938 | Biological process | coenzyme A catabolic process |
| GO_0045087 | Biological process | innate immune response |
| GO_0098552 | Cellular component | side of membrane |
| GO_0035577 | Cellular component | azurophil granule membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0017159 | Molecular function | pantetheine hydrolase activity |
| Gene name | VNN1 |
| Protein name | Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) (Vanin-1) |
| Synonyms | |
| Description | FUNCTION: Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. . |
| Accessions | ENST00000367928.5 O95497 |
