FCGR1A | OmnibusX

Name	Number of supported studies	Average coverage
macrophage	20 studies	30% ± 11%	Explore
classical monocyte	19 studies	29% ± 10%	Explore
monocyte	10 studies	31% ± 18%	Explore
non-classical monocyte	10 studies	23% ± 7%	Explore
microglial cell	7 studies	45% ± 26%	Explore
conventional dendritic cell	6 studies	22% ± 6%	Explore
myeloid cell	6 studies	28% ± 8%	Explore
alveolar macrophage	4 studies	24% ± 3%	Explore
dendritic cell	3 studies	19% ± 1%	Explore
mononuclear phagocyte	3 studies	20% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of FCGR1A at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	98%	370.49	568 / 578	78%	5.33	898 / 1155
brain	71%	234.59	1867 / 2642	95%	17.40	668 / 705
kidney	56%	69.33	50 / 89	73%	5.74	656 / 901
breast	41%	45.64	186 / 459	87%	5.59	978 / 1118
adrenal gland	86%	159.12	223 / 258	30%	1.39	68 / 230
ovary	28%	24.99	51 / 180	78%	5.15	334 / 430
pancreas	28%	28.41	93 / 328	70%	3.75	124 / 178
spleen	97%	463.73	233 / 241	0%	0	0 / 0
bladder	48%	64.05	10 / 21	43%	2.78	215 / 504
uterus	27%	25.34	46 / 170	57%	3.28	261 / 459
thymus	43%	45.31	284 / 653	40%	1.64	241 / 605
lymph node	0%	0	0 / 0	83%	18.43	24 / 29
peripheral blood	81%	2649.90	756 / 929	0%	0	0 / 0
blood vessel	79%	219.42	1055 / 1335	0%	0	0 / 0
stomach	22%	24.77	78 / 359	49%	2.79	141 / 286
skin	4%	3.48	74 / 1809	66%	5.87	313 / 472
intestine	36%	39.78	346 / 966	34%	1.75	181 / 527
prostate	57%	60.62	140 / 245	11%	0.32	56 / 502
adipose	66%	124.30	794 / 1204	0%	0	0 / 0
esophagus	20%	19.87	289 / 1445	45%	1.83	82 / 183
tonsil	0%	0	0 / 0	62%	3.32	28 / 45
liver	27%	29.91	62 / 226	21%	1.18	85 / 406
heart	33%	36.82	280 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	19%	0.96	15 / 80
muscle	1%	0.89	10 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0050766	Biological process	positive regulation of phagocytosis
GO_0006898	Biological process	receptor-mediated endocytosis
GO_0045087	Biological process	innate immune response
GO_0007165	Biological process	signal transduction
GO_0001805	Biological process	positive regulation of type III hypersensitivity
GO_0006911	Biological process	phagocytosis, engulfment
GO_0006955	Biological process	immune response
GO_0006910	Biological process	phagocytosis, recognition
GO_0001788	Biological process	antibody-dependent cellular cytotoxicity
GO_0042742	Biological process	defense response to bacterium
GO_0042590	Biological process	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO_0038094	Biological process	Fc-gamma receptor signaling pathway
GO_0001798	Biological process	positive regulation of type IIa hypersensitivity
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0031901	Cellular component	early endosome membrane
GO_0030669	Cellular component	clathrin-coated endocytic vesicle membrane
GO_0019770	Molecular function	IgG receptor activity
GO_0019864	Molecular function	IgG binding
GO_0005515	Molecular function	protein binding
GO_0019771	Molecular function	high-affinity IgG receptor activity

Gene name	FCGR1A
Protein name	High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64) Fc gamma receptor Ia
Synonyms	FCGR1 IGFR1 FCG1
Description	FUNCTION: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. .
Accessions	C9JSN8 ENST00000444948.5 ENST00000369168.5 [P12314-1] P12314

FCGR1A report