KLRG1 report

II. Expression across tissues

III. Associated gene sets

GO_0006954Biological processinflammatory response
GO_0006968Biological processcellular defense response
GO_0045087Biological processinnate immune response
GO_0007166Biological processcell surface receptor signaling pathway
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0016020Cellular componentmembrane
GO_0005886Cellular componentplasma membrane
GO_0038023Molecular functionsignaling receptor activity
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKLRG1
Protein nameKiller cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)
Killer cell lectin like receptor G1
SynonymsMAFAL
MAFA
CLEC15A
DescriptionFUNCTION: Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. .

AccessionsQ96E93
F5H207
ENST00000356986.8 [Q96E93-2]
ENST00000543895.1
ENST00000539240.5
F5H8E3
ENST00000266551.8 [Q96E93-1]