Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 17 studies | 22% ± 6% | |
memory B cell | 13 studies | 23% ± 5% | |
naive B cell | 6 studies | 22% ± 4% | |
microglial cell | 4 studies | 22% ± 6% |
Insufficient scRNA-seq data for expression of TLR10 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 86% | 105.39 | 2263 / 2642 | 77% | 2.91 | 540 / 705 |
lung | 98% | 119.87 | 564 / 578 | 62% | 3.17 | 721 / 1155 |
breast | 49% | 25.76 | 225 / 459 | 52% | 1.88 | 577 / 1118 |
lymph node | 0% | 0 | 0 / 0 | 100% | 40.52 | 29 / 29 |
spleen | 100% | 3623.44 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 2774.38 | 920 / 929 | 0% | 0 | 0 / 0 |
kidney | 45% | 36.92 | 40 / 89 | 42% | 1.04 | 382 / 901 |
prostate | 66% | 57.52 | 162 / 245 | 21% | 0.48 | 103 / 502 |
stomach | 48% | 36.75 | 174 / 359 | 32% | 1.87 | 91 / 286 |
intestine | 54% | 427.86 | 517 / 966 | 20% | 1.10 | 106 / 527 |
tonsil | 0% | 0 | 0 / 0 | 71% | 4.56 | 32 / 45 |
thymus | 31% | 78.46 | 200 / 653 | 32% | 1.45 | 196 / 605 |
pancreas | 21% | 8.60 | 70 / 328 | 39% | 1.90 | 70 / 178 |
esophagus | 33% | 30.08 | 476 / 1445 | 25% | 0.89 | 46 / 183 |
bladder | 38% | 44.81 | 8 / 21 | 19% | 0.83 | 98 / 504 |
liver | 48% | 19.22 | 108 / 226 | 10% | 0.81 | 39 / 406 |
adipose | 49% | 34.56 | 591 / 1204 | 0% | 0 | 0 / 0 |
skin | 15% | 5.06 | 279 / 1809 | 31% | 2.11 | 144 / 472 |
uterus | 17% | 7.39 | 29 / 170 | 23% | 0.67 | 104 / 459 |
adrenal gland | 27% | 8.82 | 70 / 258 | 2% | 0.02 | 4 / 230 |
ovary | 5% | 2.15 | 9 / 180 | 17% | 0.31 | 75 / 430 |
blood vessel | 19% | 19.27 | 247 / 1335 | 0% | 0 | 0 / 0 |
heart | 10% | 4.60 | 86 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 0.10 | 3 / 80 |
muscle | 1% | 0.31 | 7 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006955 | Biological process | immune response |
GO_0002224 | Biological process | toll-like receptor signaling pathway |
GO_0006954 | Biological process | inflammatory response |
GO_0071221 | Biological process | cellular response to bacterial lipopeptide |
GO_0045087 | Biological process | innate immune response |
GO_0043235 | Cellular component | receptor complex |
GO_0016020 | Cellular component | membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0035663 | Molecular function | Toll-like receptor 2 binding |
GO_0005515 | Molecular function | protein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0071723 | Molecular function | lipopeptide binding |
GO_0061809 | Molecular function | NAD+ nucleotidase, cyclic ADP-ribose generating |
Gene name | TLR10 |
Protein name | Toll-like receptor 10 (CD antigen CD290) Toll like receptor 10 TLR10 |
Synonyms | UNQ315/PRO358 |
Description | FUNCTION: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). . |
Accessions | D6RHW6 ENST00000622002.4 D1CS29 ENST00000508334.1 D1CS20 Q9BXR5 D1CS28 ENST00000308973.9 ENST00000506111.1 D1CS27 ENST00000613579.4 D1CS24 D1CS30 D1CS19 D1CS26 ENST00000502321.5 ENST00000361424.6 |