Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 13 studies | 26% ± 12% | |
| type II pneumocyte | 6 studies | 20% ± 6% | |
| epithelial cell | 4 studies | 23% ± 5% | |
| hepatocyte | 4 studies | 41% ± 15% | |
| club cell | 4 studies | 19% ± 2% | |
| adipocyte | 3 studies | 24% ± 6% | |
| mesothelial cell | 3 studies | 26% ± 6% | |
| adventitial cell | 3 studies | 23% ± 3% | |
| astrocyte | 3 studies | 23% ± 1% |
Insufficient scRNA-seq data for expression of C1RL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 11769.50 | 226 / 226 | 100% | 66.00 | 406 / 406 |
| ovary | 100% | 6599.34 | 180 / 180 | 100% | 35.04 | 429 / 430 |
| lung | 100% | 4819.12 | 577 / 578 | 100% | 40.88 | 1151 / 1155 |
| breast | 100% | 5659.37 | 459 / 459 | 99% | 35.69 | 1110 / 1118 |
| intestine | 100% | 3966.80 | 966 / 966 | 99% | 21.60 | 520 / 527 |
| bladder | 100% | 5367.00 | 21 / 21 | 98% | 30.66 | 496 / 504 |
| uterus | 100% | 4734.26 | 170 / 170 | 97% | 27.11 | 447 / 459 |
| thymus | 100% | 3296.54 | 651 / 653 | 98% | 25.45 | 590 / 605 |
| prostate | 100% | 4389.09 | 245 / 245 | 97% | 32.79 | 488 / 502 |
| esophagus | 99% | 4961.77 | 1436 / 1445 | 98% | 24.65 | 179 / 183 |
| stomach | 98% | 3376.58 | 353 / 359 | 99% | 21.39 | 282 / 286 |
| pancreas | 96% | 3050.20 | 314 / 328 | 98% | 42.38 | 175 / 178 |
| kidney | 91% | 2685.24 | 81 / 89 | 93% | 38.42 | 835 / 901 |
| skin | 99% | 3059.76 | 1789 / 1809 | 74% | 14.05 | 351 / 472 |
| adrenal gland | 100% | 10785.77 | 258 / 258 | 70% | 17.17 | 160 / 230 |
| adipose | 100% | 5599.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4845.23 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4567.29 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 24.03 | 44 / 45 |
| peripheral blood | 90% | 4852.53 | 833 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 16.65 | 25 / 29 |
| heart | 71% | 1287.18 | 608 / 861 | 0% | 0 | 0 / 0 |
| brain | 13% | 160.05 | 347 / 2642 | 52% | 12.62 | 367 / 705 |
| eye | 0% | 0 | 0 / 0 | 56% | 7.19 | 45 / 80 |
| muscle | 50% | 687.68 | 403 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006958 | Biological process | complement activation, classical pathway |
| GO_0045087 | Biological process | innate immune response |
| GO_0031638 | Biological process | zymogen activation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | C1RL |
| Protein name | Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa) Complement C1r subcomponent like C1RL protein |
| Synonyms | C1RLP C1RL1 CLSPA |
| Description | FUNCTION: Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. . |
| Accessions | ENST00000671752.1 ENST00000537833.6 ENST00000539803.5 H0YGP8 Q9NZP8 H0YFL7 Q6P672 ENST00000266542.9 ENST00000545337.1 F5H7C8 ENST00000544702.5 F5H6S5 ENST00000545280.5 ENST00000534969.2 H0YF87 F5H2Z5 ENST00000543933.5 H0YFJ9 ENST00000534950.1 F5GWF3 |
