SERINC5 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	19 studies	26% ± 8%	Explore
endothelial cell	17 studies	35% ± 15%	Explore
oligodendrocyte	15 studies	44% ± 19%	Explore
oligodendrocyte precursor cell	14 studies	50% ± 21%	Explore
astrocyte	13 studies	29% ± 11%	Explore
macrophage	13 studies	30% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	29% ± 12%	Explore
T cell	11 studies	27% ± 10%	Explore
fibroblast	11 studies	26% ± 6%	Explore
type I pneumocyte	9 studies	36% ± 12%	Explore
GABAergic neuron	9 studies	38% ± 18%	Explore
epithelial cell	9 studies	48% ± 20%	Explore
endothelial cell of lymphatic vessel	9 studies	36% ± 14%	Explore
adipocyte	8 studies	30% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	25% ± 9%	Explore
myeloid cell	7 studies	30% ± 10%	Explore
interneuron	6 studies	41% ± 18%	Explore
basal cell	6 studies	34% ± 19%	Explore
club cell	6 studies	35% ± 12%	Explore
type II pneumocyte	6 studies	31% ± 10%	Explore
monocyte	6 studies	29% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	21% ± 4%	Explore
glutamatergic neuron	5 studies	37% ± 14%	Explore
microglial cell	5 studies	29% ± 12%	Explore
dendritic cell	5 studies	27% ± 4%	Explore
lymphocyte	5 studies	28% ± 10%	Explore
Mueller cell	5 studies	45% ± 9%	Explore
T follicular helper cell	5 studies	24% ± 4%	Explore
podocyte	4 studies	40% ± 15%	Explore
regulatory T cell	4 studies	19% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 8%	Explore
luminal cell of prostate epithelium	4 studies	45% ± 16%	Explore
secretory cell	4 studies	30% ± 6%	Explore
CD8-positive, alpha-beta T cell	4 studies	24% ± 6%	Explore
conventional dendritic cell	3 studies	28% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	25% ± 7%	Explore
GABAergic interneuron	3 studies	25% ± 4%	Explore
squamous epithelial cell	3 studies	37% ± 26%	Explore
ciliated cell	3 studies	38% ± 17%	Explore
hepatocyte	3 studies	68% ± 18%	Explore
ependymal cell	3 studies	38% ± 10%	Explore
respiratory goblet cell	3 studies	34% ± 6%	Explore
alveolar macrophage	3 studies	39% ± 11%	Explore
pericyte	3 studies	30% ± 5%	Explore
smooth muscle cell	3 studies	19% ± 3%	Explore
goblet cell	3 studies	39% ± 30%	Explore
transit amplifying cell	3 studies	38% ± 29%	Explore
brush cell	3 studies	30% ± 10%	Explore
neuron	3 studies	50% ± 24%	Explore
mucus secreting cell	3 studies	32% ± 5%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	14 studies	34% ± 18%	Explore
lung	7 studies	28% ± 7%	Explore
peripheral blood	3 studies	21% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	99%	4716.23	243 / 245	99%	121.30	498 / 502
intestine	100%	2547.68	963 / 966	98%	48.98	519 / 527
stomach	100%	1705.92	358 / 359	98%	45.15	281 / 286
lung	100%	2581.67	577 / 578	95%	27.03	1102 / 1155
ovary	99%	4451.47	179 / 180	94%	22.21	405 / 430
brain	95%	2231.90	2502 / 2642	99%	60.00	697 / 705
breast	100%	1980.54	458 / 459	93%	25.91	1043 / 1118
liver	100%	4782.73	226 / 226	93%	31.80	377 / 406
pancreas	97%	1199.37	319 / 328	94%	25.99	167 / 178
skin	100%	3589.17	1809 / 1809	91%	28.50	428 / 472
bladder	95%	2439.24	20 / 21	94%	36.22	474 / 504
esophagus	91%	2348.69	1311 / 1445	98%	34.78	180 / 183
uterus	100%	1725.93	170 / 170	88%	25.36	405 / 459
thymus	100%	1526.04	650 / 653	77%	14.14	467 / 605
adrenal gland	100%	8736.76	258 / 258	63%	24.58	146 / 230
kidney	99%	1307.30	88 / 89	58%	9.16	524 / 901
adipose	100%	1890.20	1203 / 1204	0%	0	0 / 0
spleen	99%	1107.27	238 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	26.95	42 / 45
heart	87%	912.55	753 / 861	0%	0	0 / 0
blood vessel	82%	764.39	1098 / 1335	0%	0	0 / 0
peripheral blood	67%	759.43	626 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	35%	5.34	28 / 80
lymph node	0%	0	0 / 0	17%	1.72	5 / 29
muscle	9%	61.05	69 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1