Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 26 studies | 32% ± 15% | |
| macrophage | 19 studies | 37% ± 20% | |
| endothelial cell of lymphatic vessel | 17 studies | 43% ± 18% | |
| astrocyte | 14 studies | 31% ± 14% | |
| endothelial cell | 10 studies | 35% ± 13% | |
| smooth muscle cell | 9 studies | 37% ± 26% | |
| connective tissue cell | 8 studies | 28% ± 15% | |
| alveolar macrophage | 7 studies | 29% ± 13% | |
| Mueller cell | 6 studies | 47% ± 24% | |
| type II pneumocyte | 6 studies | 36% ± 7% | |
| myofibroblast cell | 5 studies | 34% ± 10% | |
| mesothelial cell | 5 studies | 36% ± 9% | |
| myeloid cell | 5 studies | 39% ± 12% | |
| retinal pigment epithelial cell | 4 studies | 53% ± 18% | |
| pericyte | 3 studies | 56% ± 16% | |
| epithelial cell | 3 studies | 29% ± 12% | |
| retinal rod cell | 3 studies | 31% ± 11% | |
| ependymal cell | 3 studies | 41% ± 10% | |
| adventitial cell | 3 studies | 29% ± 6% | |
| chondrocyte | 3 studies | 31% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 89% | 1651.22 | 217 / 245 | 99% | 49.00 | 498 / 502 |
| breast | 99% | 2480.39 | 456 / 459 | 87% | 20.93 | 971 / 1118 |
| brain | 96% | 1502.88 | 2538 / 2642 | 83% | 14.06 | 582 / 705 |
| lung | 100% | 4936.14 | 577 / 578 | 75% | 13.80 | 867 / 1155 |
| skin | 96% | 2378.25 | 1731 / 1809 | 50% | 6.51 | 235 / 472 |
| thymus | 97% | 2468.27 | 635 / 653 | 36% | 4.19 | 217 / 605 |
| uterus | 99% | 4231.13 | 168 / 170 | 34% | 8.56 | 155 / 459 |
| bladder | 95% | 2925.24 | 20 / 21 | 36% | 5.09 | 179 / 504 |
| intestine | 95% | 2021.25 | 915 / 966 | 24% | 2.69 | 125 / 527 |
| esophagus | 79% | 2137.90 | 1145 / 1445 | 37% | 4.36 | 68 / 183 |
| ovary | 61% | 797.99 | 109 / 180 | 54% | 7.08 | 231 / 430 |
| stomach | 74% | 1058.60 | 265 / 359 | 33% | 3.46 | 93 / 286 |
| adipose | 100% | 4199.67 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 95% | 1845.68 | 1268 / 1335 | 0% | 0 | 0 / 0 |
| heart | 86% | 1323.44 | 743 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 14% | 93.26 | 45 / 328 | 71% | 12.57 | 126 / 178 |
| adrenal gland | 42% | 373.43 | 108 / 258 | 13% | 1.90 | 31 / 230 |
| kidney | 33% | 380.39 | 29 / 89 | 22% | 5.24 | 202 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 47% | 4.77 | 21 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 41% | 3.16 | 12 / 29 |
| muscle | 33% | 252.01 | 269 / 803 | 0% | 0 | 0 / 0 |
| spleen | 12% | 84.63 | 29 / 241 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 9% | 1.52 | 36 / 406 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.99 | 7 / 80 |
| peripheral blood | 1% | 28.05 | 13 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0009756 | Biological process | carbohydrate mediated signaling |
| GO_0045087 | Biological process | innate immune response |
| GO_0034138 | Biological process | toll-like receptor 3 signaling pathway |
| GO_0044857 | Biological process | plasma membrane raft organization |
| GO_0006910 | Biological process | phagocytosis, recognition |
| GO_0042742 | Biological process | defense response to bacterium |
| GO_0071360 | Biological process | cellular response to exogenous dsRNA |
| GO_0006952 | Biological process | defense response |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0005581 | Cellular component | collagen trimer |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0038187 | Molecular function | pattern recognition receptor activity |
| GO_0005044 | Molecular function | scavenger receptor activity |
| GO_0030169 | Molecular function | low-density lipoprotein particle binding |
| GO_0005534 | Molecular function | galactose binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | COLEC12 |
| Protein name | Collectin-12 (Collectin placenta protein 1) (CL-P1) (hCL-P1) (Nurse cell scavenger receptor 2) (Scavenger receptor class A member 4) (Scavenger receptor with C-type lectin) |
| Synonyms | SCARA4 NSR2 SRCL CLP1 |
| Description | FUNCTION: Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease. . |
| Accessions | Q5KU26 ENST00000400256.5 |